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IL1F9 Antikörper

IL1F9 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal Jussy-1 unconjugated
Produktnummer ABIN5564239
  • Target Alle IL1F9 Antikörper anzeigen
    IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
    Reaktivität
    • 26
    • 8
    • 2
    • 1
    • 1
    Human
    Wirt
    • 25
    • 7
    • 1
    Maus
    Klonalität
    • 25
    • 8
    Monoklonal
    Konjugat
    • 23
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL1F9 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 17
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Spezifität
    Recognizes human IL-36gamma.
    Kreuzreaktivität
    Human
    Reinheit
    >95 % (SDS-PAGE)
    Immunogen
    Recombinant human IL-36gamma.
    Klon
    Jussy-1
    Isotyp
    IgG1
    Top Product
    Discover our top product IL1F9 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Haltbarkeit
    12 months
  • Target
    IL1F9 (Interleukin 1 Family Member 9 (IL1F9))
    Andere Bezeichnung
    IL-36gamma (IL1F9 Produkte)
    Synonyme
    IL-1F9 antikoerper, IL-1H1 antikoerper, IL-1RP2 antikoerper, IL1E antikoerper, IL1F9 antikoerper, IL1H1 antikoerper, IL1RP2 antikoerper, Il36g antikoerper, Il1f9 antikoerper, RGD1563019 antikoerper, IL36G antikoerper, interleukin 36 gamma antikoerper, interleukin 1 family, member 9 antikoerper, interleukin 36, gamma antikoerper, interleukin-36 gamma antikoerper, IL36G antikoerper, Il1f9 antikoerper, Il36g antikoerper, LOC100065031 antikoerper
    Hintergrund
    IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1 and are inhibited by IL-36Ra. The expression of IL-36 cytokines has been shown to occur at different sites including the lung and skin and can be derived from diverse cell types including keratinocytes, bronchial epithelium as well as macrophages, monocytes and different T cell subsets. IL-36 family members induce the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 in BMDC and CD4 T cells, thus promoting neutrophil influx, dendritic cell (DC) activation, polarization of T helper type 1 (Th1) and IL-17-producing T cells (alphabeta T cells and gammadelta T cells) and keratinocyte proliferation. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination. IL-36gamma is also induced in the lung in various models of asthma and can be produced by bronchial epithelial cells in response to viral infection, smoke or inflammatory cytokines.
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