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IL1F10 Antikörper

IL1F10 Reaktivität: Human, Maus ELISA, WB Wirt: Maus Monoclonal Nhat-1 unconjugated
Produktnummer ABIN5564279
  • Target Alle IL1F10 Antikörper anzeigen
    IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))
    Reaktivität
    • 28
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 18
    • 9
    • 1
    Maus
    Klonalität
    • 18
    • 10
    Monoklonal
    Konjugat
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser IL1F10 Antikörper ist unkonjugiert
    Applikation
    • 10
    • 9
    • 5
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Spezifität
    Recognizes human and mouse IL-38.
    Kreuzreaktivität
    Human, Maus
    Reinheit
    >95 % (SDS-PAGE)
    Immunogen
    Recombinant human IL-38.
    Klon
    Nhat-1
    Isotyp
    IgG2b
    Top Product
    Discover our top product IL1F10 Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    In PBS containing 10 % glycerol and 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Haltbarkeit
    12 months
  • Target
    IL1F10 (Interleukin 1 Family, Member 10 (Theta) (IL1F10))
    Andere Bezeichnung
    IL-38 (IL1F10 Produkte)
    Synonyme
    FIL1-theta antikoerper, IL-1HY2 antikoerper, IL-38 antikoerper, IL1-theta antikoerper, IL1HY2 antikoerper, interleukin 1 family, member 10 antikoerper, interleukin 1 family member 10 antikoerper, Il1f10 antikoerper, IL1F10 antikoerper
    Hintergrund
    IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 as a IL-1 family receptor antagonist. Il-38 inhibits IL-36 signaling by binding to IL-1R6. IL-38 (aa 20-152) is released from apoptotic cells to limit inflammatory macrophage and downstream Th17 activation by blocking IL1RAPL1 (Interleukin-1 receptor accessory protein-like 1, TIGIRR-2) signaling. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.
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