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p21 Antikörper (AA 65-164)

Name: p21 Antikörper (AA 65-164)
SKU: ABIN560309
Price: 661.92 EUR
Availability: InStock

CDKN1A Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 2F1 unconjugated

CDKN1A monoclonal antibody (M02), clone 2F1. (p21 Antikörper (AA 65-164))

Immunofluorescence of monoclonal antibody to CDKN1A on HeLa cell. (p21 Antikörper (AA 65-164))

Proximity Ligation Analysis of protein-protein interactions between CASP3 and CDKN1A. (p21 Antikörper (AA 65-164))

PLA

Western Blot detection against Immunogen (36. (p21 Antikörper (AA 65-164))

Detection limit for recombinant GST tagged CDKN1A is approximately 0. (p21 Antikörper (AA 65-164))

ELISA

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN560309

Datenblatt (PDF)

Target Alle p21 (CDKN1A) Antikörper anzeigen

p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))
Bindungsspezifität
36

30

16

15

15

10

8

8

8

7

7

7

7

7

6

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 65-164
Reaktivität
240

121

97

36

13

11

5

4

2

1

1

1

1

1

1
Human
Wirt
208

51

1
Maus
Passende Sekundärantikörper
Klonalität
202

57

1
Monoklonal
Konjugat
104

17

15

15

10

8

5

5

5

5

5

5

5

5

5

5

5

3

3

3

3

3

3

3

3

3

3

3

3
Dieser p21 Antikörper ist unkonjugiert
Applikation
158

92

67

66

66

56

52

42

41

33

20

14

13

5

2

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Proximity Ligation Assay (PLA)

Verwendungszweck

Mouse monoclonal antibody raised against a partial recombinant CDKN1A.

Sequenz

WERVRGLGLP KLYLPTGPRR GRDELGGGRR PGTSPALLQG TAEEDHVDLS LSCTLVPRSG EQAEGSPGGP GDSQGRKRRQ TSMTDFYHSK RRLIFSKRKP

Kreuzreaktivität

Human

Produktmerkmale

Antibody Reactive Against Recombinant Protein.

Immunogen

CDKN1A (AAH00312.1, 65 a.a. ~ 164 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon

2F1

Isotyp

IgG1

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

In 1x PBS, pH 7.4

Handhabung

Aliquot to avoid repeated freezing and thawing.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Massimi, Cardarelli, Galli, Giardi, Ragusa, Panera, Cinque, Cifone, Biagioni, Giorgi: "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." in: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).

Huang, Chuang, Hao, Talbot, Sen, Trink, Sidransky, Ratovitski: "Phospho-?Np63? is a key regulator of the cisplatin-induced microRNAome in cancer cells." in: Cell death and differentiation, Vol. 18, Issue 7, pp. 1220-30, (2011) (PubMed).
Target

p21 (CDKN1A) (Cyclin-Dependent Kinase Inhibitor 1A (p21, Cip1) (CDKN1A))

Andere Bezeichnung

CDKN1A (CDKN1A Produkte)

Hintergrund

Full Gene Name: cyclin-dependent kinase inhibitor 1A (p21, Cip1)
Synonyms: CAP20,CDKN1,CIP1,MDA-6,P21,SDI1,WAF1,p21CIP1

Gen-ID

1026

NCBI Accession

NM_000389

Pathways

p53 Signalweg, PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Mitotic G1-G1/S Phases, DNA Replication, Hepatitis C, Synthesis of DNA, Autophagie