CTH Antikörper (AA 1-405)

Produktnummer ABIN560523

Produktdetails anti-CTH Antikörper

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Bindungsspezifität: AA 1-405

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant CTH.

Sequenz: MQEKDASSQG FLPHFQHFAT QAIHVGQDPE QWTSRAVVPP ISLSTTFKQG APGQHSGFEY SRSGNPTRNC LEKAVAALDG AKYCLAFASG LAATVTITHL LKAGDQIICM DDVYGGTNRY FRQVASEFGL KISFVDCSKI KLLEAAITPE TKLVWIETPT NPTQKVIDIE GCAHIVHKHG DIILVVDNTF MSPYFQRPLA LGADISMYSA TKYMNGRSDV VMGLVSVNCE SLHNRLRFLQ NSLGAVPSPI DCYLCNRGLK TLHVRMEKHF KNGMAVAQFL ESNPWVEKVI YPGLPSHPQH ELVKRQCTGC TGMVTFYIKG TLQHAEIFLK NLKLFTLAES LGGFESLAEL PAIMTHASVL KNDRDVLGIS DTLIRLSVGL EDEEDLLEDL DQALKAAHPP SGSHS

Kreuzreaktivität: Human, Maus

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: CTH (AAH15807, 1 a.a. ~ 405 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: S51

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-CTH Antikörper (ABIN560523)

Ohmura, Hishiki, Yamamoto, Nakanishi, Kubo, Tsuchihashi, Tamada, Toue, Kabe, Saya, Suematsu: "Impacts of CD44 knockdown in cancer cells on tumor and host metabolic systems revealed by quantitative imaging mass spectrometry." in: Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society, Vol. 46, pp. 102-13, (2015) (PubMed).

Bucci, Papapetropoulos, Vellecco, Zhou, Zaid, Giannogonas, Cantalupo, Dhayade, Karalis, Wang, Feil, Cirino: "cGMP-dependent protein kinase contributes to hydrogen sulfide-stimulated vasorelaxation." in: PLoS ONE, Vol. 7, Issue 12, pp. e53319, (2013) (PubMed).

Guo, Gai, Wang, Jin, Du, Jin: "Characterization of hydrogen sulfide and its synthases, cystathionine ?-synthase and cystathionine ?-lyase, in human prostatic tissue and cells." in: Urology, Vol. 79, Issue 2, pp. 483.e1-5, (2012) (PubMed).

Streeter, Hart, Badoer: "An investigation of the mechanisms of hydrogen sulfide-induced vasorelaxation in rat middle cerebral arteries." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 385, Issue 10, pp. 991-1002, (2012) (PubMed).

Zhang, Yang, Untereiner, Ju, Wu, Wang: "Hydrogen sulfide impairs glucose utilization and increases gluconeogenesis in hepatocytes." in: Endocrinology, Vol. 154, Issue 1, pp. 114-26, (2012) (PubMed).

Zhu, Liu, Liu, Wang, Ni: "Glucocorticoids suppress cystathionine gamma-lyase expression and H2S production in lipopolysaccharide-treated macrophages." in: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 7, pp. 1119-32, (2010) (PubMed).

Siebert, Cantré, Eipel, Vollmar: "H2S contributes to the hepatic arterial buffer response and mediates vasorelaxation of the hepatic artery via activation of K(ATP) channels." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 295, Issue 6, pp. G1266-73, (2008) (PubMed).

Details zu CTH

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Andere Bezeichnung: CTH (CTH Produkte)

Hintergrund: Full Gene Name: cystathionase (cystathionine gamma-lyase)
Synonyms: MGC9471

Gen-ID: 1491

Pathways: ER-Nucleus Signaling, Warburg Effekt