Dihydrofolate Reductase Antikörper (AA 88-187)

Produktnummer ABIN560600

Produktdetails anti-Dihydrofolate Reductase Antikörper

Target: Dihydrofolate Reductase (DHFR)

Bindungsspezifität: AA 88-187

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Dihydrofolate Reductase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant DHFR.

Sequenz: HFLSRSLDDA LKLTEQPELA NKVDMVWIVG GSSVYKEAMN HPGHLKLFVT RIMQDFESDT FFPEIDLEKY KLLPEYPGVL SDVQEEKGIK YKFEVYEKND

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: DHFR (AAH03584, 88 a.a. ~ 187 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 2B10

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-Dihydrofolate Reductase Antikörper (ABIN560600)

Jabs, Oelze, Mikhed, Stamm, Kröller-Schön, Welschof, Jansen, Hausding, Kopp, Steven, Schulz, Stasch, Münzel, Daiber: "Effect of soluble guanylyl cyclase activator and stimulator therapy on nitroglycerin-induced nitrate tolerance in rats." in: Vascular pharmacology, Vol. 71, pp. 181-91, (2015) (PubMed).

Kossmann, Hu, Steven, Schönfelder, Fraccarollo, Mikhed, Brähler, Knorr, Brandt, Karbach, Becker, Oelze, Bauersachs, Widder, Münzel, Daiber, Wenzel: "Inflammatory monocytes determine endothelial nitric-oxide synthase uncoupling and nitro-oxidative stress induced by angiotensin II." in: The Journal of biological chemistry, Vol. 289, Issue 40, pp. 27540-50, (2014) (PubMed).

Oelze, Kröller-Schön, Welschof, Jansen, Hausding, Mikhed, Stamm, Mader, Zinßius, Agdauletova, Gottschlich, Steven, Schulz, Bottari, Mayoux, Münzel, Daiber et al.: "The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozotocin diabetes rat model by interfering with oxidative stress and ..." in: PLoS ONE, Vol. 9, Issue 11, pp. e112394, (2014) (PubMed).

Vodenicharov, Laterreur, Wellinger: "Telomere capping in non-dividing yeast cells requires Yku and Rap1." in: The EMBO journal, Vol. 29, Issue 17, pp. 3007-19, (2010) (PubMed).

Yoon, Choi, Kim, Shin, Zhang, Kang: "Influence of reduced folate carrier and dihydrofolate reductase genes on methotrexate-induced cytotoxicity." in: Cancer research and treatment : official journal of Korean Cancer Association, Vol. 42, Issue 3, pp. 163-71, (2010) (PubMed).

Ionova, Vásquez-Vivar, Whitsett, Herrnreiter, Medhora, Cooley, Pieper: "Deficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytes." in: American journal of physiology. Heart and circulatory physiology, Vol. 295, Issue 5, pp. H2178-87, (2008) (PubMed).

Details zu Dihydrofolate Reductase

Target: Dihydrofolate Reductase (DHFR)

Andere Bezeichnung: DHFR (DHFR Produkte)

Synonyme: DHFR antikoerper, F10_orf160 antikoerper, ECK0049 antikoerper, JW0047 antikoerper, tmrA antikoerper, cb595 antikoerper, zgc:86637 antikoerper, DDBDRAFT_0187132 antikoerper, DDBDRAFT_0230113 antikoerper, DDB_0187132 antikoerper, DDB_0230113 antikoerper, CG14887 antikoerper, Dmel\\CG14887 antikoerper, dhfr antikoerper, DHFRP1 antikoerper, DYR antikoerper, 8430436I03Rik antikoerper, AA607882 antikoerper, AI662710 antikoerper, AW555094 antikoerper, Dhfr1 antikoerper, confers resistance to sulfonamides antikoerper, dihydrofolate reductase antikoerper, dihydrofolate reductase DhfR antikoerper, Dihydrofolate reductase antikoerper, dhfr antikoerper, DHFR antikoerper, dhfR antikoerper, folA antikoerper, dfrA antikoerper, LOC707382 antikoerper, CNJ01940 antikoerper, DDB_G0286755 antikoerper, Dhfr antikoerper, Mesil_0096 antikoerper, Arch_0408 antikoerper, Fbal_3367 antikoerper, Ilyop_0482 antikoerper, Lbys_2007 antikoerper, Riean_0733 antikoerper, Mrub_1855 antikoerper, Poras_0766 antikoerper, Halhy_3552 antikoerper, Mesop_3614 antikoerper, LOC609048 antikoerper

Hintergrund: Full Gene Name: dihydrofolate reductase
Synonyms:

Gen-ID: 1719

Pathways: Mitotic G1-G1/S Phases