Fatty Acid Synthase Antikörper (AA 1-439)

Produktnummer ABIN560848

Produktdetails anti-Fatty Acid Synthase Antikörper

Target: Fatty Acid Synthase (FASN)

Bindungsspezifität: AA 1-439

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fatty Acid Synthase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant FASN.

Sequenz: MSTNDTIVSG TLPQRMASCL EVLDLFLNQP HMVLSSFVLA EKAAAYRDRD SQRDLVEAVA HILGIRDLAA VNLDSSLADL GLDSLMSVEV RQTLERELNL VLSVREVRQL TLRKLQELSS KADEASELAC PTPKEDGLAQ QQTQLNLRSL LVNPEGPTLM RLNSVQSSER PLFLVHPIEG STTVFHSLAS GLSIPTYGLQ CTRAAPLDSI HSLAAYYIDC IRQVQPEGPY RVAGYSYGAC VAFEMCSQLQ AQQSPAPTHN SLFLFDGSPT YVLAYTQSYR AKLTPGCEAE AETEAICFFV QQFTDMEHNR VLEALLPLKG LEERVAAAVD LIIKSHQGLD RQELSFAARS FYYKLRAAEQ YTPKAKYHGN VMLLRAKTGG AYGEDLGADY NLSQVCDGKV SVHVIEGDHR TLLEGSGLES IISIIHSSLA EPRVSVREG

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: FASN (AAH07909, 1 a.a. ~ 439 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 3F2-1F3

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-Fatty Acid Synthase Antikörper (ABIN560848)

Meller, Bicker, Montani, Ikenberg, Rostamzadeh, Sailer, Wild, Dietrich, Uhl, Sulser, Moch, Gorr, Stephan, Jung, Hankeln, Kristiansen: "Myoglobin expression in prostate cancer is correlated to androgen receptor expression and markers of tumor hypoxia." in: Virchows Archiv : an international journal of pathology, Vol. 465, Issue 4, pp. 419-27, (2014) (PubMed).

Gorr, Wichmann, Pilarsky, Theurillat, Fabrizius, Laufs, Bauer, Koslowski, Horn, Burmester, Hankeln, Kristiansen: "Old proteins - new locations: myoglobin, haemoglobin, neuroglobin and cytoglobin in solid tumours and cancer cells." in: Acta physiologica (Oxford, England), Vol. 202, Issue 3, pp. 563-81, (2011) (PubMed).

Kristiansen, Rose, Geisler, Fritzsche, Gerhardt, Lüke, Ladhoff, Knüchel, Dietel, Moch, Varga, Theurillat, Gorr, Dahl: "Endogenous myoglobin in human breast cancer is a hallmark of luminal cancer phenotype." in: British journal of cancer, Vol. 102, Issue 12, pp. 1736-45, (2010) (PubMed).

Details zu Fatty Acid Synthase

Target: Fatty Acid Synthase (FASN)

Andere Bezeichnung: FASN (FASN Produkte)

Hintergrund: Full Gene Name: fatty acid synthase
Synonyms: FAS,MGC14367,MGC15706,OA-519,SDR27X1

Gen-ID: 2194

Pathways: AMPK Signaling