Glutaminase Antikörper (AA 580-669)

Produktnummer ABIN561056

Produktdetails anti-Glutaminase Antikörper

Target: Glutaminase (GLS)

Bindungsspezifität: AA 580-669

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Glutaminase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant GLS.

Sequenz: EQRDYDSRTA LHVAAAEGHV EVVKFLLEAC KVNPFPKDRW NNTPMDEALH FGHHDVFKIL QEYQVQYTPQ GDSDNGKENQ TVHKNLDGLL

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: GLS (NP_055720, 580 a.a. ~ 669 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 5C4

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-Glutaminase Antikörper (ABIN561056)

Reynolds, Lane, Robertson, Kemp, Liu, Hill, Dean, Clem: "Control of glutamine metabolism by the tumor suppressor Rb." in: Oncogene, Vol. 33, Issue 5, pp. 556-66, (2014) (PubMed).

Hida, Mouri, Ando, Mori, Mamiya, Iwamoto, Ozaki, Yamada, Nabeshima, Noda: "Combination of neonatal PolyI:C and adolescent phencyclidine treatments is required to induce behavioral abnormalities with overexpression of GLAST in adult mice." in: Behavioural brain research, Vol. 258, pp. 34-42, (2013) (PubMed).

Cassago, Ferreira, Ferreira, Fornezari, Gomes, Greene, Pereira, Garratt, Dias, Ambrosio: "Mitochondrial localization and structure-based phosphate activation mechanism of Glutaminase C with implications for cancer metabolism." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 4, pp. 1092-7, (2012) (PubMed).

Unterluggauer, Mazurek, Lener, Hütter, Eigenbrodt, Zwerschke, Jansen-Dürr: "Premature senescence of human endothelial cells induced by inhibition of glutaminase." in: Biogerontology, Vol. 9, Issue 4, pp. 247-59, (2008) (PubMed).

Details zu Glutaminase

Target: Glutaminase (GLS)

Andere Bezeichnung: GLS (GLS Produkte)

Synonyme: Glut antikoerper, RATGLUT antikoerper, gls antikoerper, si:dz87i4.2 antikoerper, wu:fa97e05 antikoerper, GA antikoerper, PAG antikoerper, AAD20 antikoerper, GAC antikoerper, GAM antikoerper, GLS1 antikoerper, KGA antikoerper, AI314027 antikoerper, 6330442B14 antikoerper, B230365M23Rik antikoerper, CG8772 antikoerper, CG8872 antikoerper, Dmel\\CG42708 antikoerper, Dmel_CG8772 antikoerper, BA3155 antikoerper, glutaminase antikoerper, glutaminase b antikoerper, Glutaminase antikoerper, glutaminase kidney isoform, mitochondrial antikoerper, Gls antikoerper, GLS antikoerper, gls antikoerper, glsb antikoerper, glsA2 antikoerper, glsA-2 antikoerper, Arnit_3113 antikoerper, Celal_2913 antikoerper, Celly_0289 antikoerper, Weevi_2101 antikoerper, Mesop_4683 antikoerper, LOC100069617 antikoerper

Hintergrund: Full Gene Name: glutaminase
Synonyms: AAD20,DKFZp686O15119,FLJ10358,GLS1,KIAA0838

Gen-ID: 2744

NCBI Accession: NM_014905

Pathways: Feeding Behaviour, Dicarboxylic Acid Transport, Warburg Effekt