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eIF4EBP1 Antikörper (pSer65)

EIF4EBP1 Reaktivität: Human IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 1E2E7 unconjugated
Produktnummer ABIN5611114
  • Target Alle eIF4EBP1 (EIF4EBP1) Antikörper anzeigen
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    Bindungsspezifität
    • 28
    • 20
    • 19
    • 18
    • 16
    • 15
    • 11
    • 10
    • 10
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer65
    Reaktivität
    • 222
    • 168
    • 123
    • 21
    • 14
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 234
    • 18
    • 4
    Maus
    Klonalität
    • 224
    • 34
    Monoklonal
    Konjugat
    • 104
    • 23
    • 17
    • 11
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    Dieser eIF4EBP1 Antikörper ist unkonjugiert
    Applikation
    • 200
    • 83
    • 78
    • 67
    • 66
    • 42
    • 22
    • 22
    • 16
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Verwendungszweck
    Phospho-4E-BP1 (Ser65) Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Synthesized peptide of human Phospho-4E-BP1 (Ser65).
    Klon
    1E2E7
    Isotyp
    IgG1
    Top Product
    Discover our top product EIF4EBP1 Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/100 - 1/500

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
    Andere Bezeichnung
    4E-BP1 (EIF4EBP1 Produkte)
    Synonyme
    4E-BP1 antikoerper, 4EBP1 antikoerper, BP-1 antikoerper, PHAS-I antikoerper, 4e-bp1 antikoerper, AA959816 antikoerper, 153432_at antikoerper, 43-BP antikoerper, 4E-BP antikoerper, 4EBP antikoerper, 4e-bp antikoerper, 4eBP antikoerper, 4ebp antikoerper, BcDNA.HL08053 antikoerper, BcDNA:HL08053 antikoerper, CG8846 antikoerper, CT8705 antikoerper, Dm 4E-BP antikoerper, Dmel\\CG8846 antikoerper, Phas1 antikoerper, Thor/EIF4EBP antikoerper, anon-WO0172774.158 antikoerper, d4E-BP antikoerper, d4E-BP1 antikoerper, d4EBP antikoerper, d4e-bp antikoerper, d4eBP antikoerper, dthor antikoerper, eIF4E-BP antikoerper, l(2)06270 antikoerper, l(2)k07736 antikoerper, l(2)k13517 antikoerper, pp20 antikoerper, thor antikoerper, EIF4EBP1 antikoerper, fc04h09 antikoerper, wu:fc04h09 antikoerper, zgc:64137 antikoerper, eukaryotic translation initiation factor 4E binding protein 1 antikoerper, CG8846 gene product from transcript CG8846-RA antikoerper, EIF4EBP1 antikoerper, Eif4ebp1 antikoerper, Thor antikoerper, eif4ebp1 antikoerper
    Hintergrund

    Description: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

    Aliases: EIF4EBP1, BP-1, 4EBP1, 4E-BP1, PHAS-I

    Molekulargewicht
    12.6kDa
    Gen-ID
    1978
    HGNC
    1978
    UniProt
    Q13541
    Pathways
    MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Regulation of Cell Size, BCR Signaling
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