eIF4EBP1 Antikörper (pSer65)
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- Target Alle eIF4EBP1 (EIF4EBP1) Antikörper anzeigen
- eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
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Bindungsspezifität
- pSer65
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser eIF4EBP1 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Verwendungszweck
- Phospho-4E-BP1 (Ser65) Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Synthesized peptide of human Phospho-4E-BP1 (Ser65).
- Klon
- 1E2E7
- Isotyp
- IgG1
- Top Product
- Discover our top product EIF4EBP1 Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/100 - 1/500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- eIF4EBP1 (EIF4EBP1) (Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1))
- Andere Bezeichnung
- 4E-BP1 (EIF4EBP1 Produkte)
- Hintergrund
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Description: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Aliases: EIF4EBP1, BP-1, 4EBP1, 4E-BP1, PHAS-I
- Molekulargewicht
- 12.6kDa
- Gen-ID
- 1978
- HGNC
- 1978
- UniProt
- Q13541
- Pathways
- MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, AMPK Signaling, Regulation of Cell Size, BCR Signaling
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