Adenosine A2a Receptor Antikörper (AA 274-412)
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- Target Alle Adenosine A2a Receptor (ADORA2A) Antikörper anzeigen
- Adenosine A2a Receptor (ADORA2A)
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Bindungsspezifität
- AA 274-412
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Adenosine A2a Receptor Antikörper ist unkonjugiert
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Applikation
- ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Verwendungszweck
- ADORA2A Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human ADORA2A (AA: 274-412) expressed in E. Coli.
- Klon
- 6A6G11
- Isotyp
- IgG2a
- Top Product
- Discover our top product ADORA2A Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/100 - 1/500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- Adenosine A2a Receptor (ADORA2A)
- Andere Bezeichnung
- ADORA2A (ADORA2A Produkte)
- Synonyme
- ADORA2A antikoerper, adora2a.1 antikoerper, zgc:194773 antikoerper, A2aR antikoerper, ADORA2 antikoerper, RDC8 antikoerper, A2AAR antikoerper, AA2AR antikoerper, A2ar antikoerper, ADENO antikoerper, Adora2l1 antikoerper, adora2a.2 antikoerper, zgc:193802 antikoerper, zgc:193822 antikoerper, adenosine A2a receptor antikoerper, adenosine A2a receptor a antikoerper, adenosine A2a receptor L homeolog antikoerper, adenosine A2a receptor b antikoerper, ADORA2A antikoerper, Adora2a antikoerper, adora2aa antikoerper, adora2a.L antikoerper, adora2a antikoerper, adora2ab antikoerper
- Hintergrund
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Description: This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily, which is subdivided into classes and subtypes. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein, an adenosine receptor of A2A subtype, uses adenosine as the preferred endogenous agonist and preferentially interacts with the G(s) and G(olf) family of G proteins to increase intracellular cAMP levels. It plays an important role in many biological functions, such as cardiac rhythm and circulation, cerebral and renal blood flow, immune function, pain regulation, and sleep. It has been implicated in pathophysiological conditions such as inflammatory diseases and neurodegenerative disorders. Alternative splicing results in multiple transcript variants. A read-through transcript composed of the upstream SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.
Aliases: A2aR, RDC8, ADORA2
- Molekulargewicht
- 44.7kDa
- Gen-ID
- 135
- HGNC
- 135
- UniProt
- P29274
- Pathways
- Neurotrophin Signalübertragung, cAMP Metabolic Process, Synaptic Membrane, Feeding Behaviour, Cancer Immune Checkpoints
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