BCR Antikörper (AA 139-280)
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- Target Alle BCR Antikörper anzeigen
- BCR (Breakpoint Cluster Region (BCR))
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Bindungsspezifität
- AA 139-280
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser BCR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- BCR Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human BCR (AA: 139-280) expressed in E. Coli.
- Klon
- 1E11G12
- Isotyp
- IgG1
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anti-Breakpoint Cluster Region (BCR) (AA 182-280) antibody
BCR Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 2E5 unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr360) antibodyBCR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr177) antibodyBCR Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 1-300) antibodyBCR Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 1-1076) antibodyBCR Reaktivität: Human WB, PLA Wirt: Kaninchen Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (N-Term) antibodyBCR Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (AA 331-380), (pTyr360) antibodyBCR Reaktivität: Human, Maus WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr177) antibodyBCR Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (Ser178) antibodyBCR Reaktivität: Human, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Breakpoint Cluster Region (BCR) (pTyr177) antibodyBCR Reaktivität: Human WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- BCR (Breakpoint Cluster Region (BCR))
- Andere Bezeichnung
- BCR (BCR Produkte)
- Synonyme
- si:dkey-83d9.7 antikoerper, zK83D9.7 antikoerper, BCR antikoerper, ALL antikoerper, BCR1 antikoerper, CML antikoerper, D22S11 antikoerper, D22S662 antikoerper, PHL antikoerper, 5133400C09Rik antikoerper, AI561783 antikoerper, AI853148 antikoerper, mKIAA3017 antikoerper, breakpoint cluster region antikoerper, BCR, RhoGEF and GTPase activating protein antikoerper, bcr antikoerper, BCR antikoerper, Bcr antikoerper
- Hintergrund
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Description: A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Aliases: ALL, CML, PHL, BCR1, D22S11, D22S662
- Molekulargewicht
- 142.8kDa
- Gen-ID
- 613
- HGNC
- 613
- UniProt
- P11274
- Pathways
- Regulation of Leukocyte Mediated Immunity, Platelet-derived growth Factor Receptor Signaling
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