GRM2 Antikörper (AA 414-558)

Produktnummer ABIN5611158

Produktdetails anti-GRM2 Antikörper

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Bindungsspezifität: AA 414-558

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GRM2 Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Verwendungszweck: GRM2 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human GRM2 (AA: 414-558) expressed in E. Coli.

Klon: 4A10B9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu GRM2

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Andere Bezeichnung: GRM2 (GRM2 Produkte)

Synonyme: GLUR2 antikoerper, GPRC1B antikoerper, MGLUR2 antikoerper, mGlu2 antikoerper, 4930441L02Rik antikoerper, Gprc1b antikoerper, mGluR2 antikoerper, mGluR7 antikoerper, glutamate metabotropic receptor 2 antikoerper, glutamate receptor, metabotropic 2 antikoerper, GRM2 antikoerper, Grm2 antikoerper

Hintergrund:

Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.

Aliases: GLUR2, mGlu2, GPRC1B, MGLUR2

Molekulargewicht: 95.6kDa

Gen-ID: 2912

HGNC: 2912

UniProt: Q14416

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport