GRM8 Antikörper (AA 440-583)
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- Target Alle GRM8 Antikörper anzeigen
- GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
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Bindungsspezifität
- AA 440-583
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser GRM8 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- GRM8 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human GRM8 (AA: 440-583) expressed in E. Coli.
- Klon
- 4C1C1
- Isotyp
- IgG1
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anti-Glutamate Receptor, Metabotropic 8 (GRM8) antibody
GRM8 Reaktivität: Human WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (N-Term) antibodyGRM8 Reaktivität: Human, Maus, Ratte, Affe, Kaninchen, Fledermaus, Pferd, Huhn, Hund, Hamster, Schaf IHC, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (C-Term) antibodyGRM8 Reaktivität: Human, Maus, Ratte, Affe, Fledermaus, Pferd IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 486-575) antibodyGRM8 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4A7 unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 486-575) antibodyGRM8 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) antibodyGRM8 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 841-890) antibodyGRM8 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (Extracellular Domain), (N-Term) antibodyGRM8 Reaktivität: Human IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Glutamate Receptor, Metabotropic 8 (GRM8) (AA 365-377), (Extracellular), (N-Term) antibodyGRM8 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- GRM8 (Glutamate Receptor, Metabotropic 8 (GRM8))
- Andere Bezeichnung
- GRM8 (GRM8 Produkte)
- Hintergrund
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Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Aliases: GLUR8, mGlu8, GPRC1H, MGLUR8
- Molekulargewicht
- 101.7kDa
- Gen-ID
- 2918
- HGNC
- 2918
- UniProt
- O00222
- Pathways
- cAMP Metabolic Process, Synaptic Membrane
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