IL9 Receptor Antikörper (AA 41-270)

Produktnummer ABIN5611174

Produktdetails anti-IL9 Receptor Antikörper

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Bindungsspezifität: AA 41-270

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL9 Receptor Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Verwendungszweck: CD129 Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CD129 (AA: 41-270) expressed in E. Coli.

Klon: 4A11H2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu IL9 Receptor

Target: IL9 Receptor (IL9R) (Interleukin 9 Receptor (IL9R))

Andere Bezeichnung: CD129 (IL9R Produkte)

Synonyme: CD129 antikoerper, IL-9R antikoerper, interleukin 9 receptor antikoerper, IL9R antikoerper, Il9r antikoerper

Hintergrund:

Description: The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as well as the interleukin 2 receptor, gamma (IL2RG), a common gamma subunit shared by the receptors of many different cytokines. The ligand binding of this receptor leads to the activation of various JAK kinases and STAT proteins, which connect to different biologic responses. This gene is located at the pseudoautosomal regions of X and Y chromosomes. Genetic studies suggested an association of this gene with the development of asthma. Multiple pseudogenes on chromosome 9, 10, 16, and 18 have been described. Alternatively spliced transcript variants have been found for this gene.

Aliases: IL9R, IL-9R

Molekulargewicht: 57.1kDa

Gen-ID: 3581

HGNC: 3581

UniProt: Q01113

Pathways: JAK-STAT Signalweg, Growth Factor Binding