Metabotropic Glutamate Receptor 3 Antikörper (AA 433-576)
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- Target Alle Metabotropic Glutamate Receptor 3 (GRM3) Antikörper anzeigen
- Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
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Bindungsspezifität
- AA 433-576
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Metabotropic Glutamate Receptor 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human GRM3 (AA: extra 433-576) expressed in E. coli.
- Klon
- 7A5A6
- Isotyp
- IgG2a
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
- Andere Bezeichnung
- GRM3 (GRM3 Produkte)
- Synonyme
- GLUR3 antikoerper, GPRC1C antikoerper, MGLUR3 antikoerper, mGlu3 antikoerper, 0710001G23Rik antikoerper, Gprc1c antikoerper, mGluR3 antikoerper, glutamate metabotropic receptor 3 antikoerper, glutamate receptor, metabotropic 3 antikoerper, GRM3 antikoerper, Grm3 antikoerper
- Hintergrund
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Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Aliases: GLUR3, mGlu3, GPRC1C, MGLUR3
- Molekulargewicht
- 99 kDa
- Gen-ID
- 2913
- HGNC
- 2913
- Pathways
- cAMP Metabolic Process, Synaptic Membrane
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