Axin Antikörper (AA 546-752)
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- Target Alle Axin (AXIN1) Antikörper anzeigen
- Axin (AXIN1) (Axin 1 (AXIN1))
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Bindungsspezifität
- AA 546-752
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Axin Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Verwendungszweck
- AXIN1 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human AXIN1 (AA: 546-752) expressed in E. Coli.
- Klon
- 4E9F1
- Isotyp
- IgG2b
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/50 - 1/250
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- Axin (AXIN1) (Axin 1 (AXIN1))
- Andere Bezeichnung
- AXIN1 (AXIN1 Produkte)
- Synonyme
- AXIN1 antikoerper, axin antikoerper, fused antikoerper, xAxin antikoerper, LOC100226467 antikoerper, AXIN antikoerper, PPP1R49 antikoerper, AI316800 antikoerper, Axin antikoerper, Fu antikoerper, Kb antikoerper, Ki antikoerper, kinky antikoerper, knobbly antikoerper, AXIN1-RGS antikoerper, wu:fi22e03 antikoerper, wu:fj14c08 antikoerper, wu:fk11b03 antikoerper, zgc:109872 antikoerper, axin 1 antikoerper, axin 1 S homeolog antikoerper, axin 1 L homeolog antikoerper, AXIN1 antikoerper, axin1.S antikoerper, axin1.L antikoerper, Axin1 antikoerper, axin1 antikoerper
- Hintergrund
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Description: This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Alternative splicing results in multiple transcript variants.
Aliases: AXIN, PPP1R49
- Molekulargewicht
- 95.6kDa
- Gen-ID
- 8312
- HGNC
- 8312
- UniProt
- O15169
- Pathways
- WNT Signalweg, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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