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PRKAB2 Antikörper (AA 1-120)
PRKAB2
Reaktivität: Human
WB, IHC, ELISA, FACS, ICC, Neut
Wirt: Maus
Monoclonal
7A8C3
unconjugated
Produktnummer ABIN5611225
Produktdetails anti-PRKAB2 Antikörper
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Target
Alle PRKAB2 Antikörper anzeigen
PRKAB2
(Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
Bindungsspezifität
Alle Epitope für PRKAB2 Antikörper
AA 1-120
Reaktivität
Alle Reaktivitäten für PRKAB2 Antikörper
Human
Wirt
Alle Wirte für PRKAB2 Antikörper
Maus
Klonalität
Alle Klonalitäten für PRKAB2 Antikörper
Monoklonal
Konjugat
Alle Konjugate für PRKAB2 Antikörper
Dieser PRKAB2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für PRKAB2 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
Aufreinigung
purified
Immunogen
Purified recombinant fragment of human PRKAB2 (AA: 1-120) expressed in E. coli.
Klon
7A8C3
Isotyp
IgG2b
Top Product
Discover our top product PRKAB2 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Purified antibody in PBS with 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
4°C, -20°C for long term storage
Details zu PRKAB2
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Target
PRKAB2
(Protein Kinase, AMP-Activated, beta 2 Non-Catalytic Subunit (PRKAB2))
Andere Bezeichnung
PRKAB2 (PRKAB2 Produkte )
Synonyme
prkab2 antikoerper, MGC64365 antikoerper, PRKAB2 antikoerper, DKFZp469M1118 antikoerper, 5730553K21Rik antikoerper, AW049591 antikoerper, BB124140 antikoerper, protein kinase, AMP-activated, beta 2 non-catalytic subunit L homeolog antikoerper, protein kinase AMP-activated non-catalytic subunit beta 2 antikoerper, protein kinase, AMP-activated, beta 2 non-catalytic subunit antikoerper, prkab2.L antikoerper, PRKAB2 antikoerper, prkab2 antikoerper, Prkab2 antikoerper
Hintergrund
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
Molekulargewicht
30.3 kDa
Gen-ID
5565
HGNC
5565
Pathways
AMPK Signaling , Warburg Effekt
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