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BCL6 Antikörper (AA 147-276)

BCL6 Reaktivität: Human FACS, ELISA, ICC Wirt: Maus Monoclonal 2G1B6 unconjugated
Produktnummer ABIN5611253
  • Target Alle BCL6 Antikörper anzeigen
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    Bindungsspezifität
    • 28
    • 11
    • 10
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 147-276
    Reaktivität
    • 120
    • 60
    • 26
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 69
    • 49
    • 2
    • 1
    Maus
    Klonalität
    • 63
    • 58
    Monoklonal
    Konjugat
    • 68
    • 10
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Dieser BCL6 Antikörper ist unkonjugiert
    Applikation
    • 66
    • 37
    • 35
    • 32
    • 31
    • 15
    • 14
    • 11
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Immunocytochemistry (ICC)
    Verwendungszweck
    BCL6 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human BCL6 (AA: 147-276) expressed in E. Coli.
    Klon
    2G1B6
    Isotyp
    IgG1
    Top Product
    Discover our top product BCL6 Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
    Andere Bezeichnung
    BCL6 (BCL6 Produkte)
    Hintergrund

    Description: The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.

    Aliases: BCL5, LAZ3, BCL6A, ZNF51, ZBTB27

    Molekulargewicht
    78.8kDa
    Gen-ID
    604
    HGNC
    604
    UniProt
    P41182
    Pathways
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
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