CCR1 Antikörper
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- Target Alle CCR1 Antikörper anzeigen
- CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CCR1 Antikörper ist unkonjugiert
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Applikation
- ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- CD191 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD191 (AA: mix) expressed in E. Coli.
- Klon
- 8E10G6
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- CCR1 (Chemokine (C-C Motif) Receptor 1 (CCR1))
- Andere Bezeichnung
- CD191 (CCR1 Produkte)
- Synonyme
- CD191 antikoerper, CKR-1 antikoerper, CKR1 antikoerper, CMKBR1 antikoerper, HM145 antikoerper, MIP1aR antikoerper, SCYAR1 antikoerper, Cmkbr1 antikoerper, Mip-1a-R antikoerper, C-C motif chemokine receptor 1 antikoerper, chemokine (C-C motif) receptor 1 antikoerper, CCR1 antikoerper, Ccr1 antikoerper
- Hintergrund
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Description: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
Aliases: CCR1, CKR1, CKR-1, HM145, CMKBR1, MIP1aR, SCYAR1
- Molekulargewicht
- 41.2kDa
- Gen-ID
- 1230
- HGNC
- 1230
- UniProt
- P32246
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