CCR3 Antikörper
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- Target Alle CCR3 Antikörper anzeigen
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CCR3 Antikörper ist unkonjugiert
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Applikation
- ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- CD193 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human CD193 (AA: mix) expressed in E. Coli.
- Klon
- 8E9H10
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- CCR3 (Chemokine (C-C Motif) Receptor 3 (CCR3))
- Andere Bezeichnung
- CD193 (CCR3 Produkte)
- Synonyme
- CC-CKR-3 antikoerper, CD193 antikoerper, CKR3 antikoerper, CMKBR3 antikoerper, CC-CKR3 antikoerper, Cmkbr1l2 antikoerper, Cmkbr3 antikoerper, C-C motif chemokine receptor 3 antikoerper, chemokine (C-C motif) receptor 3 antikoerper, CCR3 antikoerper, Ccr3 antikoerper
- Hintergrund
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Description: The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.
Aliases: CKR3, CCR3, CMKBR3, CC-CKR-3
- Molekulargewicht
- 41kDa
- Gen-ID
- 1232
- HGNC
- 1232
- UniProt
- P51677
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