CD276 Antikörper (AA 29-466)
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- Target Alle CD276 Antikörper anzeigen
- CD276
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Bindungsspezifität
- AA 29-466
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD276 Antikörper ist unkonjugiert
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Applikation
- ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- Verwendungszweck
- B7H3 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human B7H3 (AA: 29-466) expressed in HEK293 cells.
- Klon
- 8C1C2
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/100 - 1/500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- CD276
- Andere Bezeichnung
- B7H3 (CD276 Produkte)
- Synonyme
- sc:d0645 antikoerper, zgc:158279 antikoerper, 6030411F23Rik antikoerper, AU016588 antikoerper, B7RP-2 antikoerper, B7h3 antikoerper, B7H3 antikoerper, 4Ig-B7-H3 antikoerper, B7-H3 antikoerper, CD276 molecule antikoerper, CD276 molecule S homeolog antikoerper, CD276 antigen antikoerper, Cd276 molecule antikoerper, CD276 antikoerper, cd276.S antikoerper, cd276 antikoerper, Cd276 antikoerper
- Hintergrund
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Description: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Aliases: CD276, B7-H3, B7RP-2, 4Ig-B7-H3
- Molekulargewicht
- 57.2kDa
- Gen-ID
- 80381
- HGNC
- 80381
- UniProt
- Q5ZPR3
- Pathways
- Cancer Immune Checkpoints
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