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CD276 Antikörper (AA 29-466)

CD276 Reaktivität: Human ELISA, FACS, IHC, ICC Wirt: Maus Monoclonal 8C1C2 unconjugated
Produktnummer ABIN5611271
  • Target Alle CD276 Antikörper anzeigen
    CD276
    Bindungsspezifität
    • 15
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 29-466
    Reaktivität
    • 65
    • 36
    • 9
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 47
    • 17
    • 9
    • 1
    Maus
    Klonalität
    • 43
    • 30
    • 1
    Monoklonal
    Konjugat
    • 38
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD276 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 22
    • 22
    • 14
    • 13
    • 9
    • 8
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Verwendungszweck
    B7H3 Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human B7H3 (AA: 29-466) expressed in HEK293 cells.
    Klon
    8C1C2
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/100 - 1/500

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Target
    CD276
    Andere Bezeichnung
    B7H3 (CD276 Produkte)
    Synonyme
    sc:d0645 antikoerper, zgc:158279 antikoerper, 6030411F23Rik antikoerper, AU016588 antikoerper, B7RP-2 antikoerper, B7h3 antikoerper, B7H3 antikoerper, 4Ig-B7-H3 antikoerper, B7-H3 antikoerper, CD276 molecule antikoerper, CD276 molecule S homeolog antikoerper, CD276 antigen antikoerper, Cd276 molecule antikoerper, CD276 antikoerper, cd276.S antikoerper, cd276 antikoerper, Cd276 antikoerper
    Hintergrund

    Description: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    Aliases: CD276, B7-H3, B7RP-2, 4Ig-B7-H3

    Molekulargewicht
    57.2kDa
    Gen-ID
    80381
    HGNC
    80381
    UniProt
    Q5ZPR3
    Pathways
    Cancer Immune Checkpoints
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