DDR1 Antikörper (AA 21-176)

Produktnummer ABIN5611283

Produktdetails anti-DDR1 Antikörper

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Bindungsspezifität: AA 21-176

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DDR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human CD167 (AA: extra 21-176) expressed in E. coli.

Klon: 4F2C12

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: N/A, FCM: 1:200 - 1:400, IHC: N/A

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu DDR1

Target: DDR1 (Discoidin Domain Receptor tyrosine Kinase 1 (DDR1))

Andere Bezeichnung: CD167 (DDR1 Produkte)

Synonyme: CG11573 antikoerper, CG13984 antikoerper, CG13985 antikoerper, CG33531 antikoerper, CG9488 antikoerper, CG9490 antikoerper, CT33540 antikoerper, DDR antikoerper, Dmel\\CG33531 antikoerper, Dmel_CG13984 antikoerper, 6030432F18 antikoerper, AI323681 antikoerper, CD167a antikoerper, Cak antikoerper, Nep antikoerper, PTK3A antikoerper, CAK antikoerper, CD167 antikoerper, EDDR1 antikoerper, HGK2 antikoerper, MCK10 antikoerper, NEP antikoerper, NTRK4 antikoerper, PTK3 antikoerper, RTK6 antikoerper, TRKE antikoerper, Drd1 antikoerper, PTK3D antikoerper, Discoidin domain receptor antikoerper, discoidin domain receptor family, member 1 antikoerper, discoidin domain receptor tyrosine kinase 1 antikoerper, Ddr antikoerper, Ddr1 antikoerper, DDR1 antikoerper

Hintergrund:

Description: Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Aliases: DDR1,CAK, DDR, NEP, HGK2, PTK3, RTK6, TRKE, EDDR1, MCK10, NTRK4, PTK3A

Molekulargewicht: 101 kDa

Gen-ID: 780

HGNC: 780

Pathways: RTK Signalweg, Smooth Muscle Cell Migration