BCL2L10 Antikörper (AA 31-186)
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- Target Alle BCL2L10 Antikörper anzeigen
- BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
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Bindungsspezifität
- AA 31-186
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser BCL2L10 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Verwendungszweck
- BCL2L10 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human BCL2L10 (AA: 31-186) expressed in E. Coli.
- Klon
- 8A2F9
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))
- Andere Bezeichnung
- BCL2L10 (BCL2L10 Produkte)
- Synonyme
- BCL-B antikoerper, Boo antikoerper, Diva antikoerper, AA420380 antikoerper, AU023065 antikoerper, C85687 antikoerper, NR-13 antikoerper, mcl1l antikoerper, nr13 antikoerper, sb:cb78 antikoerper, BCL2 like 10 antikoerper, Bcl2-like 10 antikoerper, BCL2-like 10 (apoptosis facilitator) antikoerper, BCL2L10 antikoerper, Bcl2l10 antikoerper, bcl2l10 antikoerper
- Hintergrund
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Description: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.
Aliases: Boo, Diva, BCL-B, bcl2-L-10
- Molekulargewicht
- 22kDa
- Gen-ID
- 10017
- HGNC
- 10017
- UniProt
- Q9HD36
- Pathways
- Positive Regulation of Endopeptidase Activity
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