CHRND Antikörper (AA 22-245)

Produktnummer ABIN5611361

Produktdetails anti-CHRND Antikörper

Target: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Bindungsspezifität: AA 22-245

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CHRND Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Verwendungszweck: CHRND Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human CHRND (AA: 22-245) expressed in E. Coli.

Klon: 1H1F9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Details zu CHRND

Target: CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))

Andere Bezeichnung: CHRND (CHRND Produkte)

Hintergrund:

Description: The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.

Aliases: ACHRD, CMS2A, CMS3A, CMS3B, CMS3C, FCCMS, SCCMS

Molekulargewicht: 58.8kDa

Gen-ID: 1144

HGNC: 1144

UniProt: Q07001