Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
50 % glycerol
Handhabung
Aliquot to avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Peng: "The T-box transcription factor T-bet in immunity and autoimmunity." in: Cellular & molecular immunology, Vol. 3, Issue 2, pp. 87-95, (2006) (PubMed).
Hwang, Hong, Glimcher: "IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508." in: The Journal of experimental medicine, Vol. 202, Issue 9, pp. 1289-300, (2005) (PubMed).
Hwang, Szabo, Schwartzberg, Glimcher: "T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3." in: Science (New York, N.Y.), Vol. 307, Issue 5708, pp. 430-3, (2005) (PubMed).
Hibbert, Pflanz, De Waal Malefyt, Kastelein: "IL-27 and IFN-alpha signal via Stat1 and Stat3 and induce T-Bet and IL-12Rbeta2 in naive T cells." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 23, Issue 9, pp. 513-22, (2003) (PubMed).
Peng, Szabo, Glimcher: "T-bet regulates IgG class switching and pathogenic autoantibody production." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 8, pp. 5545-50, (2002) (PubMed).
Szabo, Kim, Costa, Zhang, Fathman, Glimcher: "A novel transcription factor, T-bet, directs Th1 lineage commitment." in: Cell, Vol. 100, Issue 6, pp. 655-69, (2000) (PubMed).