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HMGB1 Antikörper (AA 1-90)

Name: HMGB1 Antikörper (AA 1-90)
SKU: ABIN561286
Price: 630.4 EUR
Availability: InStock

HMGB1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 2F6 unconjugated

HMGB1 monoclonal antibody (M08), clone 2F6 Western Blot analysis of HMGB1 expression in Hela S3 NE . (HMGB1 Antikörper (AA 1-90))

Immunofluorescence of monoclonal antibody to HMGB1 on HeLa cell. (HMGB1 Antikörper (AA 1-90))

Immunoperoxidase of monoclonal antibody to HMGB1 on formalin-fixed paraffin-embedded human placenta. (HMGB1 Antikörper (AA 1-90))

ISt

Detection limit for recombinant GST tagged HMGB1 is approximately 0. (HMGB1 Antikörper (AA 1-90))

ELISA

Western Blot analysis of HMGB1 expression in transfected 293T cell line by HMGB1 monoclonal antibody (M08), clone 2F6. (HMGB1 Antikörper (AA 1-90))

Western Blot detection against Immunogen (35. (HMGB1 Antikörper (AA 1-90))

7 Abbildungen

(2 Referenzen)

Produktnummer ABIN561286

Datenblatt (PDF)

Target Alle HMGB1 Antikörper anzeigen

HMGB1 (High Mobility Group Box 1 (HMGB1))
Bindungsspezifität
22

16

16

10

10

8

6

6

6

4

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-90
Reaktivität
157

95

94

13

11

11

10

8

6

6

6

6

5

2

1

1

1
Human
Wirt
135

32

2

2

1

1
Maus
Passende Sekundärantikörper
Klonalität
128

45
Monoklonal
Konjugat
83

17

17

8

6

6

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1
Dieser HMGB1 Antikörper ist unkonjugiert
Applikation
137

61

47

45

31

28

27

26

20

10

9

5

2

2

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck

Mouse monoclonal antibody raised against a partial recombinant HMGB1.

Sequenz

MGKGDPKKPR GKMSSYAFFV QTCREEHKKK HPDASVNFSE FSKKCSERWK TMSAKEKGKF EDMAKADKAR YEREMKTYIP PKGETKKKFK

Kreuzreaktivität

Human

Produktmerkmale

Antibody Reactive Against Recombinant Protein.

Immunogen

HMGB1 (NP_002119, 1 a.a. ~ 90 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon

2F6

Isotyp

IgG2a

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HMGB1 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

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HMGB1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

In 1x PBS, pH 7.4

Handhabung

Aliquot to avoid repeated freezing and thawing.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Gong, Zheng, Chao, Li, Xu, Huang, Gao, Li, He: "The anti-inflammatory activity of HMGB1 A box is enhanced when fused with C-terminal acidic tail." in: Journal of biomedicine & biotechnology, Vol. 2010, pp. 915234, (2010) (PubMed).

Zhou, Huang, Poon, Chen, Chan, Ng, Guan, Watt, Lu, Yuen, Zheng: "Functional dissection of an IFN-alpha/beta receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection." in: Journal of hepatology, Vol. 51, Issue 2, pp. 322-32, (2009) (PubMed).
Target

HMGB1 (High Mobility Group Box 1 (HMGB1))

Andere Bezeichnung

HMGB1 (HMGB1 Produkte)

Synonyme

HMG1 antikoerper, HMG3 antikoerper, SBP-1 antikoerper, DEF antikoerper, HMG-1 antikoerper, Hmg1 antikoerper, amphoterin antikoerper, p30 antikoerper, hmgb1 antikoerper, ik:tdsubc_1a5 antikoerper, wu:fb23c02 antikoerper, xx:tdsubc_1a5 antikoerper, zgc:56110 antikoerper, zgc:77104 antikoerper, hmg-1 antikoerper, hmg3 antikoerper, sbp-1 antikoerper, hmg1 antikoerper, HMGB1 antikoerper, Ac2-008 antikoerper, high mobility group box 1 antikoerper, high-mobility group box 1 antikoerper, high mobility group box 1a antikoerper, high mobility group box 1 L homeolog antikoerper, high mobility group protein B1 antikoerper, HMGB1 antikoerper, Hmgb1 antikoerper, hmgb1 antikoerper, hmgb1a antikoerper, hmgb1.L antikoerper, LOC100359149 antikoerper

Hintergrund

Full Gene Name: high-mobility group box 1
Synonyms: DKFZp686A04236,HMG1,HMG3,SBP-1

Gen-ID

3146

NCBI Accession

NM_002128

Pathways

p53 Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome