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K-RAS Antikörper (AA 1-188)

Name: K-RAS Antikörper (AA 1-188)
SKU: ABIN561621
Price: 661.92 EUR
Availability: InStock

KRAS Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 3B10-2F2 unconjugated

Western Blot analysis of KRAS expression in transfected 293T cell line by KRAS monoclonal antibody (M01), clone 3B10-2F2. (K-RAS Antikörper (AA 1-188))

Detection limit for recombinant GST tagged KRAS is approximately 1ng/ml as a capture antibody. (K-RAS Antikörper (AA 1-188))

ELISA

Western Blot detection against Immunogen (46. (K-RAS Antikörper (AA 1-188))

Immunofluorescence of monoclonal antibody to KRAS on HeLa cell. (K-RAS Antikörper (AA 1-188))

KRAS monoclonal antibody (M01), clone 3B10-2F2 Western Blot analysis of KRAS expression in HeLa . (K-RAS Antikörper (AA 1-188))

5 Abbildungen

(5 Referenzen)

Produktnummer ABIN561621

Datenblatt (PDF)

Target Alle K-RAS (KRAS) Antikörper anzeigen

K-RAS (KRAS) (GTPase Kras (KRAS))
Bindungsspezifität
16

11

8

6

6

4

2

1

1

1

1

1

1

1

1
AA 1-188
Reaktivität
59

39

32

5

4

3

3

3

3

3

3

2

2

2

2

1

1

1
Human
Wirt
63

9
Maus
Passende Sekundärantikörper
Klonalität
63

9
Monoklonal
Konjugat
29

7

4

4

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser K-RAS Antikörper ist unkonjugiert
Applikation
62

28

23

13

13

12

10

6

5

4

3

1
Western Blotting (WB), ELISA, Immunofluorescence (IF)

Verwendungszweck

Mouse monoclonal antibody raised against a full length recombinant KRAS.

Sequenz

MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET CLLDILDTAG HEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHHYREQI KRVKDSEDVP MVLVGNKCDL PSRTVDTKQA QDLARSYGIP FIETSAKTRQ GVDDAFYTLV REIRKHKEKM SKDGKKKKKK SKTKCVIM

Kreuzreaktivität

Human

Produktmerkmale

Antibody Reactive Against Recombinant Protein.

Immunogen

KRAS (AAH13572, 1 a.a. ~ 188 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon

3B10-2F2

Isotyp

IgG1
anti-GTPase Kras (KRAS) (AA 16-125) antibody
KRAS Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4F3 unconjugated

anti-GTPase Kras (KRAS) (AA 146-174) antibody
KRAS Reaktivität: Human, Ratte, Maus WB, ELISA, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

anti-GTPase Kras (KRAS) (AA 2-168) antibody
KRAS Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-GTPase Kras (KRAS) (AA 25-130) antibody
KRAS Reaktivität: Human, Ratte, Maus WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-GTPase Kras (KRAS) (N-Term) antibody
KRAS Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Drosophila melanogaster, Schwein, Xenopus laevis, Fledermaus, Huhn, Hamster, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-GTPase Kras (KRAS) (pSer89) antibody
KRAS Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-GTPase Kras (KRAS) (N-Term) antibody
KRAS Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Saccharomyces cerevisiae WB Wirt: Kaninchen Polyclonal unconjugated

anti-GTPase Kras (KRAS) (AA 1-189) antibody
KRAS Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-GTPase Kras (KRAS) (AA 1-188) antibody
KRAS Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1E4-1B10 unconjugated

anti-GTPase Kras (KRAS) (C-Term) antibody
KRAS Reaktivität: Human, Ratte, Maus WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

In 1x PBS, pH 7.4

Handhabung

Aliquot to avoid repeated freezing and thawing.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Madureira, Bharadwaj, Bydoun, Garant, OConnell, Lee, Waisman: "Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10." in: Oncotarget, Vol. 7, Issue 30, pp. 47720-47737, (2016) (PubMed).

King, Bray, Galbraith, Christie, Fleming: "Evidence for aldosterone-dependent growth of renal cell carcinoma." in: International journal of experimental pathology, Vol. 95, Issue 4, pp. 244-50, (2014) (PubMed).

Ambrosini, Khanin, Carvajal, Schwartz: "Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells." in: Molecular cancer therapeutics, Vol. 13, Issue 8, pp. 2073-80, (2014) (PubMed).

Valtorta, Misale, Sartore-Bianchi, Nagtegaal, Paraf, Lauricella, Dimartino, Hobor, Jacobs, Ercolani, Lamba, Scala, Veronese, Laurent-Puig, Siena, Tejpar, Mottolese, Punt, Gambacorta, Bardelli et al.: "KRAS gene amplification in colorectal cancer and impact on response to EGFR-targeted therapy. ..." in: International journal of cancer. Journal international du cancer, Vol. 133, Issue 5, pp. 1259-65, (2013) (PubMed).

Fuentes-Calvo, Blázquez-Medela, Santos, López-Novoa, Martínez-Salgado: "Analysis of k-ras nuclear expression in fibroblasts and mesangial cells." in: PLoS ONE, Vol. 5, Issue 1, pp. e8703, (2010) (PubMed).
Target

K-RAS (KRAS) (GTPase Kras (KRAS))

Andere Bezeichnung

KRAS (KRAS Produkte)

Substanzklasse

Viral Protein

Hintergrund

Full Gene Name: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Synonyms: C-K-RAS,K-RAS2A,K-RAS2B,K-RAS4A,K-RAS4B,KI-RAS,KRAS1,KRAS2,NS3,RASK2

Gen-ID

3845