NPM1 Antikörper (AA 1-294)
NPM1
Reaktivität: Human
WB, ELISA, IF, IHC (p)
Wirt: Maus
Monoclonal
3B2
unconjugated
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Target
Alle NPM1 Antikörper anzeigen
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NPM1
(Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
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Bindungsspezifität
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AA 1-294
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Reaktivität
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Human
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Wirt
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Maus
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Klonalität
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Monoklonal
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Konjugat
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Dieser NPM1 Antikörper ist unkonjugiert
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Applikation
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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Verwendungszweck
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Mouse monoclonal antibody raised against a full length recombinant NPM1.
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Sequenz
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MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIV EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE EDAESEDEEE EDVKLLSISG KRSAPGGGSK VPQKKVKLAA DEDDDDDDEE DDDEDDDDDD FDDEEAEEKA PVKKSIRDTP AKNAQKSNQN GKDSKPSSTP RSKGQESFKK QEKTPKTPKG PSSVEDIKAK MQASIEKGGS LPKVEAKFIN YVKNCFRMTD QEAIQDLWQW RKSL
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Kreuzreaktivität
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Human
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Produktmerkmale
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Antibody Reactive Against Recombinant Protein.
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Immunogen
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NPM1 (AAH02398.1, 1 a.a. ~ 294 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
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Klon
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3B2
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Isotyp
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IgG1
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Applikationshinweise
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Optimal working dilution should be determined by the investigator.
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Beschränkungen
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Nur für Forschungszwecke einsetzbar
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Buffer
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In 1x PBS, pH 7.4
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Handhabung
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Aliquot to avoid repeated freezing and thawing.
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Lagerung
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-20 °C
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Informationen zur Lagerung
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Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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El Hajj, Dassouki, Berthier, Raffoux, Ades, Legrand, Hleihel, Sahin, Tawil, Salameh, Zibara, Darwiche, Mohty, Dombret, Fenaux, de Thé, Bazarbachi: "Retinoic acid and arsenic trioxide trigger degradation of mutated NPM1, resulting in apoptosis of AML cells." in: Blood, Vol. 125, Issue 22, pp. 3447-54, (2015) (PubMed).
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Target
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NPM1
(Nucleophosmin (Nucleolar phosphoprotein B23, Numatrin) (NPM1))
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Andere Bezeichnung
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NPM1 (NPM1 Produkte)
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Hintergrund
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Full Gene Name: nucleophosmin (nucleolar phosphoprotein B23, numatrin)
Synonyms: B23,MGC104254,NPM
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Gen-ID
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4869
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Pathways
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Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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