SLC11A2
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
In 1x PBS, pH 7.4
Handhabung
Aliquot to avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Montalbetti, Simonin, Simonin, Awale, Reymond, Hediger: "Discovery and characterization of a novel non-competitive inhibitor of the divalent metal transporter DMT1/SLC11A2." in: Biochemical pharmacology, Vol. 96, Issue 3, pp. 216-24, (2015) (PubMed).
Montalbetti, Simonin, Dalghi, Kovacs, Hediger: "Development and Validation of a Fast and Homogeneous Cell-Based Fluorescence Screening Assay for Divalent Metal Transporter 1 (DMT1/SLC11A2) Using the FLIPR Tetra." in: Journal of biomolecular screening, Vol. 19, Issue 6, pp. 900-908, (2014) (PubMed).
Howitt, Putz, Lackovic, Doan, Dorstyn, Cheng, Yang, Chan-Ling, Silke, Kumar, Tan: "Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 36, pp. 15489-94, (2009) (PubMed).
Foot, Dalton, Shearwin-Whyatt, Dorstyn, Tan, Yang, Kumar: "Regulation of the divalent metal ion transporter DMT1 and iron homeostasis by a ubiquitin-dependent mechanism involving Ndfips and WWP2." in: Blood, Vol. 112, Issue 10, pp. 4268-75, (2008) (PubMed).
Target
SLC11A2
(Solute Carrier Family 11 (Proton-Coupled Divalent Metal Ion Transporters), Member 2 (SLC11A2))