PDK3 Antikörper (AA 174-263)

Produktnummer ABIN562161

Produktdetails anti-PDK3 Antikörper

Target: PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

Bindungsspezifität: AA 174-263

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PDK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant PDK3.

Sequenz: GDTNPVHPKH IGSIDPTCNV ADVVKDAYET AKMLCEQYYL VAPELEVEEF NAKAPDKPIQ VVYVPSHLFH MLFELFKNSM RATVELYEDR

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: PDK3 (AAH15948, 174 a.a. ~ 263 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 2B11

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-PDK3 Antikörper (ABIN562161)

Hwang, Wu, Harris: "Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat diet." in: The FEBS journal, Vol. 279, Issue 10, pp. 1883-93, (2012) (PubMed).

Jeoung, Harris: "Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice." in: American journal of physiology. Endocrinology and metabolism, Vol. 295, Issue 1, pp. E46-54, (2008) (PubMed).

Lu, Lin, Chen, Lai, Tsai: "Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance." in: The Journal of biological chemistry, Vol. 283, Issue 42, pp. 28106-14, (2008) (PubMed).

Details zu PDK3

Target: PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

Andere Bezeichnung: PDK3 (PDK3 Produkte)

Synonyme: pdk3 antikoerper, PDK3 antikoerper, 2610001M10Rik antikoerper, AI035637 antikoerper, zgc:158702 antikoerper, pyruvate dehydrogenase kinase 3 antikoerper, pyruvate dehydrogenase kinase, isozyme 3a antikoerper, pyruvate dehydrogenase kinase, isoenzyme 3 antikoerper, fragile site, 5-azacytidine type, common, fra(1)(q12) antikoerper, pyruvate dehydrogenase kinase, isozyme 3b antikoerper, PDK3 antikoerper, Pdk3 antikoerper, pdk3a antikoerper, pdk3 antikoerper, FRA1J antikoerper, pdk3b antikoerper

Hintergrund: Full Gene Name: pyruvate dehydrogenase kinase, isozyme 3
Synonyms:

Gen-ID: 5165

Pathways: PI3K-Akt Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt