Topoisomerase I Antikörper (AA 692-765)
-
- Target Alle Topoisomerase I (TOP1) Antikörper anzeigen
- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
-
Bindungsspezifität
- AA 692-765
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Topoisomerase I Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Mouse monoclonal antibody raised against a partial recombinant TOP1.
- Sequenz
- QRLEEQLMKL EVQATDREEN KQIALGTSKL NYLDPRITVA WCKKWGVPIE KIYNKTQREK FAWAIDMADE DYEF
- Kreuzreaktivität
- Human
- Produktmerkmale
- Antibody Reactive Against Recombinant Protein.
- Immunogen
- TOP1 (NP_003277, 692 a.a. ~ 765 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Klon
- 1A1
- Isotyp
- IgG1
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- In 1x PBS, pH 7.4
- Handhabung
- Aliquot to avoid repeated freezing and thawing.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
-
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 52, pp. 22375-80, (2010) (PubMed).
: "
-
AID-induced decrease in topoisomerase 1 induces DNA structural alteration and DNA cleavage for class switch recombination." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 52, pp. 22375-80, (2010) (PubMed).
-
- Target
- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
- Andere Bezeichnung
- TOP1 (TOP1 Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
-
Full Gene Name: topoisomerase (DNA) I
Synonyms: TOPI - Gen-ID
- 7150
- NCBI Accession
- NM_003286
- Pathways
- Caspase Kaskade in der Apoptose, Stem Cell Maintenance
-