Splicing Factor 1 Antikörper
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- Target Alle Splicing Factor 1 (SF1) Antikörper anzeigen
- Splicing Factor 1 (SF1)
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Splicing Factor 1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- Antigen affinity purified
- Immunogen
- A recombinant human protein corresponding to amino acids R160-Q266 was used as the immunogen for the SF1 antibody.
- Isotyp
- IgG
- Top Product
- Discover our top product SF1 Primärantikörper
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- Applikationshinweise
- Optimal dilution of the SF1 antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- Lagerung
- -20 °C
- Informationen zur Lagerung
- After reconstitution, the SF1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Target
- Splicing Factor 1 (SF1)
- Andere Bezeichnung
- SF1 / Splicing factor 1 (SF1 Produkte)
- Synonyme
- BBP antikoerper, D11S636 antikoerper, MBBP antikoerper, ZCCHC25 antikoerper, ZFM1 antikoerper, ZNF162 antikoerper, BB094781 antikoerper, CW17R antikoerper, MZFM antikoerper, WBP4 antikoerper, Zfp162 antikoerper, CG5836 antikoerper, Dmel\\CG5836 antikoerper, cg5836 antikoerper, dSF1 antikoerper, p70 antikoerper, SF1 antikoerper, sf1 antikoerper, wu:fc09f06 antikoerper, znf162 antikoerper, MWD22.25 antikoerper, MWD22_25 antikoerper, SF-1 antikoerper, splicing factor 1 antikoerper, Splicing factor 1 antikoerper, splicing factor-like protein antikoerper, nuclear receptor subfamily 5 group A member 1 antikoerper, splicing factor 1 S homeolog antikoerper, SF1 antikoerper, Sf1 antikoerper, sf1 antikoerper, AT5G51300 antikoerper, NR5A1 antikoerper, sf1.S antikoerper
- Hintergrund
- Splicing factor 1 also known as zinc finger protein 162 (ZFM162) is a protein that in humans is encoded by the SF1 gene. This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants.
- UniProt
- Q15637
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Maintenance of Protein Location
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