NCR3
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
The stated application concentrations are suggested starting points. Titration of the NKp30 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western Blot: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the NKp30 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Natural cytotoxicity triggering receptor 3 (NCR3), also called Natural killer cell p30-related protein (NKp30), is a cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.