ALDH7A1
Reaktivität: Human, Maus, Ratte
IF
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Western blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
-20 °C
Informationen zur Lagerung
After reconstitution, the ALDH7A1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Target
ALDH7A1
(Aldehyde Dehydrogenase 7 Family, Member A1 (ALDH7A1))
atq1 antikoerper, ALDH7A1 antikoerper, ATQ1 antikoerper, EPD antikoerper, PDE antikoerper, antiquitin antikoerper, ATQ antikoerper, wu:fi34d12 antikoerper, wu:fi35e06 antikoerper, Atq1 antikoerper, D18Wsu181e antikoerper, aldehyde dehydrogenase 7 family member A1 antikoerper, aldehyde dehydrogenase 7 family member A1 L homeolog antikoerper, aldehyde dehydrogenase 7 family, member A1 antikoerper, aldehyde dehydrogenase family 7, member A1 antikoerper, ALDH7A1 antikoerper, aldh7a1 antikoerper, aldh7a1.L antikoerper, Aldh7a1 antikoerper
Hintergrund
Aldehyde dehydrogenase 7 family, member A1, also known as ALDH7A1 or antiquitin, is an enzyme that in humans is encoded by the ALDH7A1 gene. The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism andlipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified.