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SIRT1 Antikörper (AA 456-555)

Name: SIRT1 Antikörper (AA 456-555)
SKU: ABIN565071
Price: 661.92 EUR
Availability: InStock

SIRT1 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 7B7 unconjugated

Western Blot detection against Immunogen (36. (SIRT1 Antikörper (AA 456-555))

Detection limit for recombinant GST tagged SIRT1 is approximately 0. (SIRT1 Antikörper (AA 456-555))

ELISA

SIRT1 monoclonal antibody (M01), clone 7B7 Western Blot analysis of SIRT1 expression in Hela S3 NE . (SIRT1 Antikörper (AA 456-555))

Immunofluorescence of monoclonal antibody to SIRT1 on HeLa cell. (SIRT1 Antikörper (AA 456-555))

Immunoperoxidase of monoclonal antibody to SIRT1 on formalin-fixed paraffin-embedded human lateral ventricle wall. (SIRT1 Antikörper (AA 456-555))

ISt

5 Abbildungen

(3 Referenzen)

Produktnummer ABIN565071

Datenblatt (PDF)

Target Alle SIRT1 Antikörper anzeigen

SIRT1 (Sirtuin 1 (SIRT1))
Bindungsspezifität
31

16

16

8

8

6

6

6

5

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 456-555
Reaktivität
145

88

60

34

5

3

2

2

2

2

2

1

1
Human
Wirt
130

19

2

2

1
Maus
Passende Sekundärantikörper
Klonalität
118

36
Monoklonal
Konjugat
64

13

10

4

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3

1

1
Dieser SIRT1 Antikörper ist unkonjugiert
Applikation
115

50

46

41

39

35

22

21

16

13

9

4

4

3

2

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck

Mouse monoclonal antibody raised against a partial recombinant SIRT1.

Sequenz

NRYIFHGAEV YSDSEDDVLS SSSCGSNSDS GTCQSPSLEE PMEDESEIEE FYNGLEDEPD VPERAGGAGF GTDGDDQEAI NEAISVKQEV TDMNYPSNKS

Kreuzreaktivität

Human

Produktmerkmale

Antibody Reactive Against Recombinant Protein.

Immunogen

SIRT1 (AAH12499, 456 a.a. ~ 555 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon

7B7

Isotyp

IgG1

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SIRT1 Reaktivität: Human, Maus WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Sirtuin 1 (SIRT1) (AA 456-555) antibody
SIRT1 Reaktivität: Human WB, IF, IHC (p), EIA Wirt: Maus Monoclonal 7B7 unconjugated

anti-Sirtuin 1 (SIRT1) (AA 244-498) antibody
SIRT1 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Sirtuin 1 (SIRT1) (pSer47) antibody
SIRT1 Reaktivität: Human, Maus, Ratte, Hund WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

In 1x PBS, pH 7.4

Handhabung

Aliquot to avoid repeated freezing and thawing.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Kok, Lin, Hou, Hong, Chang, Hsiao, Wang, Lai, Lin: "Simvastatin inhibits cysteine-rich protein 61 expression in rheumatoid arthritis synovial fibroblasts through the regulation of sirtuin-1/FoxO3a signaling." in: Arthritis and rheumatism, Vol. 65, Issue 3, pp. 639-49, (2013) (PubMed).

Østrup, Hyttel, Klærke, Collas: "Remodeling of ribosomal genes in somatic cells by Xenopus egg extract." in: Biochemical and biophysical research communications, Vol. 412, Issue 3, pp. 487-93, (2011) (PubMed).

Hiraike, Wada-Hiraike, Nakagawa, Koyama, Miyamoto, Sone, Tanikawa, Tsuruga, Nagasaka, Matsumoto, Oda, Shoji, Fukuhara, Saji, Nakagawa, Kato, Yano, Taketani: "Identification of DBC1 as a transcriptional repressor for BRCA1." in: British journal of cancer, Vol. 102, Issue 6, pp. 1061-7, (2010) (PubMed).
Target

SIRT1 (Sirtuin 1 (SIRT1))

Andere Bezeichnung

SIRT1 (SIRT1 Produkte)

Synonyme

sirtuin 1 antikoerper, AA673258 antikoerper, SIR2L1 antikoerper, Sir2 antikoerper, Sir2a antikoerper, Sir2alpha antikoerper, sir2l1 antikoerper, sirtuin antikoerper, SIR2 antikoerper, sirtuin 1 antikoerper, sirtuin 1 L homeolog antikoerper, SIRT1 antikoerper, SRT1 antikoerper, Sirt1 antikoerper, sirt1.L antikoerper

Hintergrund

Full Gene Name: sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae)
Synonyms: SIR2L1

Gen-ID

23411

Pathways

MAPK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Negative Regulation of intrinsic apoptotic Signaling