QPCT Antikörper (AA 262-359)

Produktnummer ABIN565166

Produktdetails anti-QPCT Antikörper

Target: QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

Bindungsspezifität: AA 262-359

Reaktivität: Human

Wirt: Maus

Klonalität: Polyklonal

Konjugat: Dieser QPCT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Mouse polyclonal antibody raised against a partial recombinant QPCT.

Sequenz: PNSARWFERL QAIEHELHEL GLLKDHSLEG RYFQNYSYGG VIQDDHIPFL RRGVPVLHLI PSPFPEVWHT MDDNEENLDE STIDNLNKIL QVFVLEYL

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: QPCT (NP_036545, 262 a.a. ~ 359 a.a) partial recombinant protein with GST tag.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 50 % glycerol

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-QPCT Antikörper (ABIN565166)

Morawski, Schilling, Kreuzberger, Waniek, Jäger, Koch, Cynis, Kehlen, Arendt, Hartlage-Rübsamen, Demuth, Roßner: "Glutaminyl cyclase in human cortex: correlation with (pGlu)-amyloid-? load and cognitive decline in Alzheimer's disease." in: Journal of Alzheimer's disease : JAD, Vol. 39, Issue 2, pp. 385-400, (2014) (PubMed).

Chen, Huang, Kuo, Lo, Lee, Wang: "Inhibition of glutaminyl cyclase attenuates cell migration modulated by monocyte chemoattractant proteins." in: The Biochemical journal, Vol. 442, Issue 2, pp. 403-12, (2012) (PubMed).

Hartlage-Rübsamen, Morawski, Waniek, Jäger, Zeitschel, Koch, Cynis, Schilling, Schliebs, Demuth, Rossner: "Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-A? deposits in hippocampus via distinct cellular mechanisms." in: Acta neuropathologica, Vol. 121, Issue 6, pp. 705-19, (2011) (PubMed).

Morawski, Hartlage-Rübsamen, Jäger, Waniek, Schilling, Schwab, McGeer, Arendt, Demuth, Rossner: "Distinct glutaminyl cyclase expression in Edinger-Westphal nucleus, locus coeruleus and nucleus basalis Meynert contributes to pGlu-Abeta pathology in Alzheimer's disease." in: Acta neuropathologica, Vol. 120, Issue 2, pp. 195-207, (2010) (PubMed).

Details zu QPCT

Target: QPCT (Glutaminyl-Peptide Cyclotransferase (QPCT))

Andere Bezeichnung: QPCT (QPCT Produkte)

Synonyme: GCT antikoerper, QC antikoerper, sQC antikoerper, QPCT antikoerper, 5730422A13Rik antikoerper, Qpctl1 antikoerper, RGD1562284 antikoerper, qpct antikoerper, glutaminyl-peptide cyclotransferase antikoerper, glutaminyl-peptide cyclotransferase (glutaminyl cyclase) antikoerper, glutaminyl-peptide cyclotransferase L homeolog antikoerper, QPCT antikoerper, Qpct antikoerper, M6_Spy0443 antikoerper, M5005_Spy_0416 antikoerper, M28_Spy0404 antikoerper, CJA_2408 antikoerper, CCNA_02733 antikoerper, Tsp_03182 antikoerper, qpct.L antikoerper

Hintergrund: Full Gene Name: glutaminyl-peptide cyclotransferase
Synonyms: GCT,QC

Gen-ID: 25797

NCBI Accession: NM_012413