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AGO2 Antikörper (AA 1-377)

AGO2 Reaktivität: Human WB, ELISA, IF, IHC (p), RNAi Wirt: Maus Monoclonal 2E12-1C9 unconjugated
Produktnummer ABIN565346
  • Target Alle AGO2 Antikörper anzeigen
    AGO2 (Argonaute 2 (AGO2))
    Bindungsspezifität
    • 8
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-377
    Reaktivität
    • 39
    • 21
    • 12
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 38
    • 3
    Maus
    Klonalität
    • 31
    • 10
    Monoklonal
    Konjugat
    • 18
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser AGO2 Antikörper ist unkonjugiert
    Applikation
    • 22
    • 16
    • 13
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), RNA Interference (RNAi)
    Verwendungszweck
    Mouse monoclonal antibody raised against a full length recombinant EIF2C2.
    Sequenz
    MPIQGQPCFC KYAQGADSVE PMFRHLKNTY AGLQLVVVIL PGKTPVYAEV KRVGDTVLGM ATQCVQMKNV QRTTPQTLSN LCLKINVKLG GVNNILLPQG RPPVFQQPVI FLGADVTHPP AGDGKKPSIA AVVGSMDAHP NRYCATVRVQ QHRQEIIQDL AAMVRELLIQ FYKSTRFKPT RIIFYRDGVS EGQFQQVLHH ELLAIREACI KLEKDYQPGI TFIVVQKRHH TRLFCTDKNE RVGKSGNIPA GTTVDTKITH PTEFDFYLCS HAGIQGTSRP SHYHVLWDDN RFSSDELQIL TYQLCHTYVR CTRSVSIPAP AYYAHLVAFR ARYHLVDKEH DSAEGSHTSG QSNGRDHQAL AKAVQVHQDT LRTMYFA
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    EIF2C2 (AAH07633.1, 483 a.a. ~ 859 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Klon
    2E12-1C9
    Isotyp
    IgG1
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1x PBS, pH 7.4
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Mantel, Hjelmqvist, Walch, Kharoubi-Hess, Nilsson, Ravel, Ribeiro, Grüring, Ma, Padmanabhan, Trachtenberg, Ankarklev, Brancucci, Huttenhower, Duraisingh, Ghiran, Kuo, Filgueira, Martinelli, Marti: "Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria." in: Nature communications, Vol. 7, pp. 12727, (2016) (PubMed).

    Wang, Ye, Wei, Han, He, Chen, Chen: "LncRNAs H19 and HULC, activated by oxidative stress, promote cell migration and invasion in cholangiocarcinoma through a ceRNA manner." in: Journal of hematology & oncology, Vol. 9, Issue 1, pp. 117, (2016) (PubMed).

    Xiao, Wang, Ni, Li, Zhang, Liu, Pu, Xu, Gao, Zhao, Mu, Wang, Sun, Du, Xu, Zhang, Hiscox, Goodfellow, Zhou: "MicroRNA miR-24-3p Promotes Porcine Reproductive and Respiratory Syndrome Virus Replication through Suppression of Heme Oxygenase-1 Expression." in: Journal of virology, Vol. 89, Issue 8, pp. 4494-503, (2015) (PubMed).

    Zhang, Guo, Gao, Huang, Li, Jia, Liu, Feng: "MicroRNA-23 inhibits PRRSV replication by directly targeting PRRSV RNA and possibly by upregulating type I interferons." in: Virology, Vol. 450-451, pp. 182-95, (2014) (PubMed).

    Nakanishi, Taccioli, Palatini, Fernandez-Cymering, Cui, Kim, Volinia, Croce: "Loss of miR-125b-1 contributes to head and neck cancer development by dysregulating TACSTD2 and MAPK pathway." in: Oncogene, Vol. 33, Issue 6, pp. 702-12, (2014) (PubMed).

    Sasaki, Gross, Xing, Goshima, Bassell: "Identification of axon-enriched microRNAs localized to growth cones of cortical neurons." in: Developmental neurobiology, Vol. 74, Issue 3, pp. 397-406, (2014) (PubMed).

    Pai, Siripornmongcolchai, Berentsen, Pakzad, Vieuille, Pallesen, Pajak, Simpson, Armstrong, Wibrand, Bramham: "NMDA receptor-dependent regulation of miRNA expression and association with Argonaute during LTP in vivo." in: Frontiers in cellular neuroscience, Vol. 7, pp. 285, (2014) (PubMed).

    Le Guillou, Marthey, Laloë, Laubier, Mobuchon, Leroux, Le Provost: "Characterisation and comparison of lactating mouse and bovine mammary gland miRNomes." in: PLoS ONE, Vol. 9, Issue 3, pp. e91938, (2014) (PubMed).

    Zhang, Zuo, Yang, Li, Xue, Zhou, Huang, Zhao, Zhou, Yan, Zhang, Guo, Sun, Guo, Zhang, Fu: "MicroRNA directly enhances mitochondrial translation during muscle differentiation." in: Cell, Vol. 158, Issue 3, pp. 607-19, (2014) (PubMed).

    Kamel, Segerman, Punga, Akusjärvi: "Small RNA sequence analysis of adenovirus VA RNA-derived miRNAs reveals an unexpected serotype-specific difference in structure and abundance." in: PLoS ONE, Vol. 9, Issue 8, pp. e105746, (2014) (PubMed).

    Llobet-Navas, Rodriguez-Barrueco, de la Iglesia-Vicente, Olivan, Castro, Saucedo-Cuevas, Marshall, Putcha, Castillo-Martin, Bardot, Ezhkova, Iavarone, Cordon-Cardo, Silva: "The microRNA 424/503 cluster reduces CDC25A expression during cell cycle arrest imposed by transforming growth factor ? in mammary epithelial cells." in: Molecular and cellular biology, Vol. 34, Issue 23, pp. 4216-31, (2014) (PubMed).

    Xue, Ouyang, Huang, Zhou, Ouyang, Li, Wang, Wu, Wei, Bi, Jiang, Cai, Sun, Zhang, Zhang, Chen, Fu: "Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits." in: Cell, Vol. 152, Issue 1-2, pp. 82-96, (2013) (PubMed).

    Wei, Nazari-Jahantigh, Chan, Zhu, Heyll, Corbalán-Campos, Hartmann, Thiemann, Weber, Schober: "The microRNA-342-5p fosters inflammatory macrophage activation through an Akt1- and microRNA-155-dependent pathway during atherosclerosis." in: Circulation, Vol. 127, Issue 15, pp. 1609-19, (2013) (PubMed).

    Laffont, Corduan, Plé, Duchez, Cloutier, Boilard, Provost: "Activated platelets can deliver mRNA regulatory Ago2•microRNA complexes to endothelial cells via microparticles." in: Blood, Vol. 122, Issue 2, pp. 253-61, (2013) (PubMed).

    Zheng, Zhang, Zhang, Wang, Ye, Xi, Du, Liang: "Single modification at position 14 of siRNA strand abolishes its gene-silencing activity by decreasing both RISC loading and target degradation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 10, pp. 4017-26, (2013) (PubMed).

    Curtale, Mirolo, Renzi, Rossato, Bazzoni, Locati: "Negative regulation of Toll-like receptor 4 signaling by IL-10-dependent microRNA-146b." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 28, pp. 11499-504, (2013) (PubMed).

    Karginov, Hannon: "Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates." in: Genes & development, Vol. 27, Issue 14, pp. 1624-32, (2013) (PubMed).

    Fan, Krutilina, Sun, Sethuraman, Yang, Wu, Yue, Pfeffer: "Comprehensive analysis of microRNA (miRNA) targets in breast cancer cells." in: The Journal of biological chemistry, Vol. 288, Issue 38, pp. 27480-93, (2013) (PubMed).

    Martinez-Sanchez, Dudek, Murphy: "Regulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145)." in: The Journal of biological chemistry, Vol. 287, Issue 2, pp. 916-24, (2012) (PubMed).

    Chiang, Sung, Rice: "Regulation of cyclin T1 and HIV-1 Replication by microRNAs in resting CD4+ T lymphocytes." in: Journal of virology, Vol. 86, Issue 6, pp. 3244-52, (2012) (PubMed).

  • Target
    AGO2 (Argonaute 2 (AGO2))
    Andere Bezeichnung
    EIF2C2 (AGO2 Produkte)
    Synonyme
    EIF2C2 antikoerper, T19E23.7 antikoerper, T19E23_7 antikoerper, argonaute 2 antikoerper, Q10 antikoerper, Eif2c2 antikoerper, Argonaute2 antikoerper, eif2c1 antikoerper, eif2c2 antikoerper, 1110029L17Rik antikoerper, 2310051F07Rik antikoerper, AI225898 antikoerper, AL022874 antikoerper, AW546247 antikoerper, ENSMUSG00000072493 antikoerper, Gerp95 antikoerper, Gm10365 antikoerper, mKIAA4215 antikoerper, AGO2 antikoerper, AG02 antikoerper, AGO 2 antikoerper, Ago-2 antikoerper, Ago2 antikoerper, CG13452 antikoerper, CG7439 antikoerper, Dm Ago2 antikoerper, Dmel\\CG7439 antikoerper, ago antikoerper, ago-2 antikoerper, ago2 antikoerper, dAGO2 antikoerper, dAgo2 antikoerper, eIF2C2 antikoerper, argonaute 2, RISC catalytic component antikoerper, Argonaute family protein antikoerper, argonaute 2, RISC catalytic component L homeolog antikoerper, argonaute RISC catalytic subunit 2 antikoerper, argonaute RISC catalytic component 2 antikoerper, Argonaute 2 antikoerper, AGO2 antikoerper, Ago2 antikoerper, ago2.L antikoerper, ago2 antikoerper
    Hintergrund
    Full Gene Name: eukaryotic translation initiation factor 2C, 2
    Synonyms: AGO2,MGC3183,Q10
    Gen-ID
    27161
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, Regulatorische RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization
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