LEF1 Antikörper (AA 1-399)

Produktnummer ABIN565556

Produktdetails anti-LEF1 Antikörper

Target: LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

Bindungsspezifität: AA 1-399

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LEF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, RNA Interference (RNAi)

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant LEF1.

Sequenz: MPQLSGGGGG GGGDPELCAT DEMIPFKDEG DPQKEKIFAE ISHPEEEGDL ADIKSSLVNE SEIIPASNGH EVARQAQTSQ EPYHDKAREH PDDGKHPDGG LYNKGPSYSS YSGYIMMPNM NNDPYMSNGS LSPPIPRTSN KVPVVQPSHA VHPLTPLITY SDEHFSPGSH PSHIPSDVNS KQGMSRHPPA PDIPTFYPLS PGGVGQITPP LGWQGQPVYP ITGGFRQPYP SSLSVDTSMS RFSHHMIPGP PGPHTTGIPH PAIVTPQVKQ EHPHTDSDLM HVKPQHEQRK EQEPKRPHIK KPLNAFMLYM KEMRANVVAE CTLKESAAIN QILGRRWHAL SREEQAKYYE LARKERQLHM QLYPGWSARD NYGKKKKRKR EKLQESASGT GPRMTAAYI

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: LEF1 (AAH50632, 1 a.a. ~ 399 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 3H5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-LEF1 Antikörper (ABIN565556)

Jamieson, Sharma, Henderson: "Regulation of ?-catenin nuclear dynamics by GSK-3? involves a LEF-1 positive feedback loop." in: Traffic (Copenhagen, Denmark), Vol. 12, Issue 8, pp. 983-99, (2011) (PubMed).

Hebenstreit, Giaisi, Treiber, Zhang, Mi, Horejs-Hoeck, Andersen, Krammer, Duschl, Li-Weber: "LEF-1 negatively controls interleukin-4 expression through a proximal promoter regulatory element." in: The Journal of biological chemistry, Vol. 283, Issue 33, pp. 22490-7, (2008) (PubMed).

Details zu LEF1

Target: LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

Andere Bezeichnung: LEF1 (LEF1 Produkte)

Synonyme: LEF1 antikoerper, 3000002B05 antikoerper, AI451430 antikoerper, Lef-1 antikoerper, LEF-1 antikoerper, TCF10 antikoerper, TCF1ALPHA antikoerper, TCF7L3 antikoerper, lymphoid enhancer binding factor 1 antikoerper, lymphoid enhancer-binding factor 1 antikoerper, lymphoid enhancer factor XLEF-1B antikoerper, LEF1 antikoerper, lef1 antikoerper, Lef1 antikoerper

Hintergrund: Full Gene Name: lymphoid enhancer-binding factor 1
Synonyms: DKFZp586H0919,TCF1ALPHA

Gen-ID: 51176

Pathways: WNT Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding