ACD Antikörper (AA 1-544)

Produktnummer ABIN566298

Produktdetails anti-ACD Antikörper

Target: ACD (Adrenocortical Dysplasia Homolog (ACD))

Bindungsspezifität: AA 1-544

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ACD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant ACD.

Sequenz: MPGRCQSDAA MRVNGPASRA PAGWTSGSLH TGPRAGRPRA QARGVRGRGL LLRPRPAKEL PLPRKGGAWA PAGNPGPLHP LGVAVGMAGS GRLVLRPWIR ELILGSETPS SPRAGQLLEV LQDAEAAVAG PSHAPDTSDV GATLLVSDGT HSVRCLVTRE ALDTSDWEEK EFGFRGTEGR LLLLQDCGVH VQVAEGGAPA EFYLQVDRFS LLPTEQPRLR VPGCNQDLDV QKKLYDCLEE HLSESTSSNA GLSLSQLLDE MREDQEHQGA LVCLAESCLT LEGPCTAPPV THWAASRCKA TGEAVYTVPS SMLCISENDQ LILSSLGPCQ RTQGPELPPP DPALQDLSLT LIASPPSSPS SSGTPALPGH MSSEESGTSI SLLPALSLAA PDPGQRSSSQ PSPAICSAPA TLTPRSPHAS RTPSSPLQSC TPSLSPRSHV PSPHQALVTR PQKPSLEFKE FVGLPCKNRP PFPRTGATRG AQEPCSVWEP PKRHRDGSAF QYEYEPPCTS LCARVQAARL PPQLMAWALH FLMDAQPGSE PTPM

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: ACD (AAH16904, 1 a.a. ~ 544 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 1D8-1B6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-ACD Antikörper (ABIN566298)

Frank, Tran, Qu, Stohr, Segal, Xu: "The Shelterin TIN2 Subunit Mediates Recruitment of Telomerase to Telomeres." in: PLoS genetics, Vol. 11, Issue 7, pp. e1005410, (2015) (PubMed).

Abreu, Aritonovska, Reichenbach, Cristofari, Culp, Terns, Lingner, Terns: "TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo." in: Molecular and cellular biology, Vol. 30, Issue 12, pp. 2971-82, (2010) (PubMed).

Details zu ACD

Target: ACD (Adrenocortical Dysplasia Homolog (ACD))

Andere Bezeichnung: ACD (ACD Produkte)

Synonyme: PIP1 antikoerper, PTOP antikoerper, TINT1 antikoerper, TPP1 antikoerper, ACD antikoerper, ACD, shelterin complex subunit and telomerase recruitment factor antikoerper, adrenocortical dysplasia antikoerper, ACD antikoerper, Acd antikoerper

Hintergrund: Full Gene Name: adrenocortical dysplasia homolog (mouse)
Synonyms: PIP1,PTOP,TINT1,TPP1

Gen-ID: 65057

Pathways: Telomere Maintenance