Calpastatin Antikörper (C-Term)

Produktnummer ABIN5663576

Produktdetails anti-Calpastatin Antikörper

Target: Calpastatin (CAST)

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calpastatin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: TIPPEYRHLL DDNGQDKPVK PPTKKSEDSK KPADDQDPID ALSGDLDSCP STTETSQNTA KDKCKKAASS SKAPKNGGKA KDSAKTTEET SKPKDD

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 600 to the C-terminus of human CAST (NP_001177371.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Calpastatin

Target: Calpastatin (CAST)

Andere Bezeichnung: CAST (CAST Produkte)

Synonyme: BS-17 antikoerper, calp3 antikoerper, CAST antikoerper, sb:cb966 antikoerper, zgc:194249 antikoerper, cast antikoerper, DKFZp469E0716 antikoerper, calpastatin antikoerper, calpastatin S homeolog antikoerper, Calpastatin antikoerper, CAST antikoerper, Cast antikoerper, cast.S antikoerper, cast antikoerper, VDBG_09182 antikoerper, ical antikoerper

Hintergrund: The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.,CAST,BS-17,PLACK,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Neuron marker,Synapse marker,CAST

Molekulargewicht: 63 kDa/71- 84 kDa

Gen-ID: 831

UniProt: P20810