Lamin B1 Antikörper
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- Target Alle Lamin B1 (LMNB1) Antikörper anzeigen
- Lamin B1 (LMNB1)
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Lamin B1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
- Aufreinigung
- Affinity purification
- Immunogen
- Fusion protein of human LMNB1
- Isotyp
- IgG
- Top Product
- Discover our top product LMNB1 Primärantikörper
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- Applikationshinweise
- Recommended dilutions: WB: 1:500-1:1000, IHC: 1:50-1:100, IF: 1:20-1:50, IP: 1:20-1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid freeze / thaw cycles
- Lagerung
- -20 °C/-80 °C
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- Target
- Lamin B1 (LMNB1)
- Andere Bezeichnung
- LMNB1 (LMNB1 Produkte)
- Synonyme
- MGC52550 antikoerper, Lamin-L(I) antikoerper, lamin-b antikoerper, lmn antikoerper, lmn2 antikoerper, lmnb antikoerper, LMNB1 antikoerper, ADLD antikoerper, LMN antikoerper, LMN2 antikoerper, LMNB antikoerper, fc06g01 antikoerper, wu:fc06g01 antikoerper, lamin B1 L homeolog antikoerper, lamin B1 antikoerper, lmnb1.L antikoerper, lmnb1 antikoerper, LMNB1 antikoerper, Lmnb1 antikoerper
- Hintergrund
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Lamins are nuclear membrane structural components that are important in maintaining normal cell functions, such as cell cycle control, DNA replication, and chromatin organization. Lamins have been subdivided into types A and B. Type-A lamins consist of lamin A and C, arising from alternative splicing. Lamin A and C are cleaved by caspases into large (41-50 kDa) and small (28 kDa) fragments, which can be used as markers for apoptosis. Type-B lamins consist of lamin B1 and B2, encoded by separate genes. Lamin B1 is also cleaved by caspases during apoptosis. Research studies have shown that duplication of the lamin B1 gene is correlated with the pathogenesis of the neurological disorder adult-onset leukodystrophy.
Synonyms: ADLD, LMN, LMN2, LMNB, MGC111419, Lamin B1 - Gen-ID
- 4001
- UniProt
- P20700
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
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