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IL2 Receptor beta Antikörper

IL2RB Reaktivität: Human FACS, IP, Func Wirt: Maus Monoclonal TU27 unconjugated
Produktnummer ABIN5665749
  • Target Alle IL2 Receptor beta (IL2RB) Antikörper anzeigen
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    Reaktivität
    • 93
    • 86
    • 16
    • 5
    • 1
    Human
    Wirt
    • 78
    • 38
    • 25
    Maus
    Klonalität
    • 79
    • 61
    • 1
    Monoklonal
    Konjugat
    • 61
    • 14
    • 11
    • 9
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL2 Receptor beta Antikörper ist unkonjugiert
    Applikation
    • 71
    • 71
    • 32
    • 26
    • 26
    • 19
    • 15
    • 10
    • 9
    • 8
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func)
    Spezifität
    The mouse monoclonal antibody TU27 recognizes an extracellular epitope of CD122 (IL-2R beta), a 70-75 kDa type I transmembrane glycoprotein constitutively expressed by NK cells and a T cell subset, and upregulated upon activation.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Endotoxin-Niveau
    Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
    Immunogen
    TL-Mor cell line
    Klon
    TU27
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product IL2RB Primärantikörper
  • Applikationshinweise
    Functional application: Blocking.
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Target
    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
    Andere Bezeichnung
    CD122 (IL2RB Produkte)
    Synonyme
    IL2RB antikoerper, il-2rb antikoerper, CD122 antikoerper, IL15RB antikoerper, P70-75 antikoerper, IL2RBC antikoerper, IL-15Rbeta antikoerper, IL15Rbeta antikoerper, Il-2/15Rbeta antikoerper, Il-2Rbeta antikoerper, p70 antikoerper, interleukin 2 receptor subunit beta antikoerper, interleukin-2 receptor subunit beta antikoerper, interleukin 2 receptor, beta antikoerper, interleukin 2 receptor, beta chain antikoerper, IL2RB antikoerper, LOC510185 antikoerper, il2rb antikoerper, Il2rb antikoerper
    Hintergrund
    Interleukin 2 receptor subunit beta,CD122 (IL-2/IL-15R beta) constitutes together with CD132 (common gamma chain) and with CD25 (IL-2/IL15R alpha) the intermediate (CD122+CD132) and the high affinity (CD122+CD132+CD25) IL-2 and IL-15 receptor complex. CD122 is expressed on NK cells and lymphocytes, but at low level, unless the cell is activated. The cytoplasmic part of CD122 binds to Src-family and Jak-family kinases. The biological effect of CD122 ligation depends on whether IL-2 or IL-15 is bound to the receptor complex.,IL2RB, IL15RB, P70-75
    Gen-ID
    3560
    UniProt
    P14784
    Pathways
    JAK-STAT Signalweg, Growth Factor Binding
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