Rekombinanter EGFR (Matuzumab Biosimilar) Antikörper (Extracellular Domain)
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- Target Alle EGFR (Matuzumab Biosimilar) Produkte
- EGFR (Matuzumab Biosimilar)
- Antikörpertyp
- Recombinant Antibody
- Bindungsspezifität
- Extracellular Domain
- Reaktivität
- Human
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Wirt
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Human
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Klonalität
- Monoklonal
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Konjugat
- Dieser EGFR (Matuzumab Biosimilar) Antikörper ist unkonjugiert
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Applikation
- Blocking Reagent (BR), Flow Cytometry (FACS), Western Blotting (WB)
- Spezifität
- Binds to human EGFR.
- Produktmerkmale
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OriginalSpeciesName: Human
OriginalFormat: IgG1
- Aufreinigung
- Purified antibody.
- Reinheit
- > 98 % as determined by SDS-PAGE
- Endotoxin-Niveau
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- Immunogen
- The parental mouse antibody was generated by immunizing BALB/c mice intraperitoneally with A431 cells in phosphate buffered saline (PBS). Later on the humanzied version of the antibody was created by grafting CDRs of the murine antibody onto human constant regions.
- Isotyp
- IgG1 kappa
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- Applikationshinweise
- This antibody binds to human EGFR at a side distinct frm the antigen binding site, preventing conformational re-arrangement required for dimerization, a process essential for high-affinitiy ligand binding (Schmiedel 2008).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- EGFR (Matuzumab Biosimilar)
- Abstract
- EGFR (Matuzumab Biosimilar) Produkte
- Hintergrund
- ErbB-1, ERBB1, HER1, EGF, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EMD72000, mAb425, 425, mAb 425
- UniProt
- P00533
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