Rekombinanter TNF alpha (Adalimumab Biosimilar) Antikörper
Reaktivität: Human
ELISA, BR, IF, IHC
Wirt: Kaninchen
Monoclonal
D2E7
unconjugated
Recombinant Antibody
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- Target Alle TNF alpha (Adalimumab Biosimilar) Produkte
- TNF alpha (Adalimumab Biosimilar)
- Antikörpertyp
- Recombinant Antibody
- Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser TNF alpha (Adalimumab Biosimilar) Antikörper ist unkonjugiert
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Applikation
- ELISA, Blocking Reagent (BR), Immunofluorescence (IF), Immunohistochemistry (IHC)
- Spezifität
- Binds to soluble TNF-alpha, but not to lymphotoxin (TNF beta).
- Produktmerkmale
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OriginalSpeciesName: Human
OriginalFormat: IgG1
- Aufreinigung
- Purified antibody.
- Reinheit
- > 98 % as determined by SDS-PAGE
- Endotoxin-Niveau
- Endotoxin is < 1.0 EU/mg as determined by the LAL method
- Immunogen
- This antibody was generated by affinity maturation from the 2SD4 scFv, which in turn was selected on human TNF alpha by guided phage-display technology, using the murine anti-hTNF alpha antibody Mab32 as a template (c.f. also US Patent 6090382).
- Klon
- D2E7
- Isotyp
- IgG kappa
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anti-TNF alpha (Adalimumab Biosimilar) antibody
Research Grade Reaktivität: Human FACS, ELISA Wirt: Human Monoclonal unconjugated Recombinant Antibody
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- Applikationshinweise
- Adalimumab binds specifically to TNF and neutralizes the biological function of TNF by blocking its interaction with the p55 and p75 cell surface TNF receptors.
- Kommentare
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NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric rabbit antibody was made using the variable domain sequences of the original human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- TNF alpha (Adalimumab Biosimilar)
- Abstract
- TNF alpha (Adalimumab Biosimilar) Produkte
- Synonyme
- DIF antikoerper, TNF-alpha antikoerper, TNFA antikoerper, TNFSF2 antikoerper, tumor necrosis factor antikoerper, TNF antikoerper
- Substanzklasse
- Biosimilar
- Hintergrund
- Tumor necrosis factor alpha
- UniProt
- P01375
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