Rekombinanter C-Type Lectin Domain Family 4, Member M (CLEC4M) Antikörper
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- Target Alle C-Type Lectin Domain Family 4, Member M (CLEC4M) Antikörper anzeigen
- C-Type Lectin Domain Family 4, Member M (CLEC4M)
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Chimeric
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Konjugat
- Unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Spezifität
- Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.
- Produktmerkmale
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OriginalSpeciesName: Mouse
OriginalFormat: IgG1
- Aufreinigung
- Purified antibody.
- Immunogen
- CD299
- Klon
- 16E7
- Isotyp
- IgG kappa
- Top Product
- Discover our top product CLEC4M Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % Proclin 300.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Target
- C-Type Lectin Domain Family 4, Member M (CLEC4M)
- Andere Bezeichnung
- DC-SIGNR (CLEC4M Produkte)
- Synonyme
- CD209L antikoerper, CD299 antikoerper, DC-SIGN2 antikoerper, DC-SIGNR antikoerper, DCSIGNR antikoerper, HP10347 antikoerper, L-SIGN antikoerper, LSIGN antikoerper, CD209B antikoerper, C-type lectin domain family 4 member M antikoerper, CLEC4M antikoerper
- Hintergrund
- CD299, C-type lectin domain family 4 member M, CD209 antigen-like protein 1, DC-SIGN-related protein, CLEC4M, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, DC-SIGN2, Liver/lymph node-specific ICAM-3-grabbing non-integrin, L-SIGN
- UniProt
- Q9H2X3
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