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Rekombinanter CD33 (Gemtuzumab Biosimilar) Antikörper

Reaktivität: Human FACS, IF Wirt: Human Monoclonal HP67-6 unconjugated Recombinant Antibody
Produktnummer ABIN5668210
  • Target Alle CD33 (Gemtuzumab Biosimilar) Produkte
    CD33 (Gemtuzumab Biosimilar)
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    Human
    Wirt
    • 1
    • 1
    • 1
    Human
    Klonalität
    • 3
    Monoklonal
    Konjugat
    • 3
    Dieser CD33 (Gemtuzumab Biosimilar) Antikörper ist unkonjugiert
    Applikation
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Spezifität
    Recognises human CD33.
    Produktmerkmale

    OriginalSpeciesName: Human

    OriginalFormat: IgG4

    Aufreinigung
    Purified antibody.
    Reinheit
    > 98 % as determined by SDS-PAGE
    Endotoxin-Niveau
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    Immunogen
    Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
    Klon
    HP67-6
    Isotyp
    IgG4 kappa
  • Applikationshinweise
    A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % Proclin 300.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    CD33 (Gemtuzumab Biosimilar)
    Abstract
    CD33 (Gemtuzumab Biosimilar) Produkte
    Synonyme
    SIGLEC-3 antikoerper, SIGLEC3 antikoerper, p67 antikoerper, CD33 molecule antikoerper, CD33 antikoerper
    Substanzklasse
    Biosimilar
    Hintergrund
    Siglec-3
    UniProt
    P20138
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