Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Rekombinanter CD33 (Gemtuzumab Biosimilar) Antikörper

Reaktivität: Human FACS, IF Wirt: Kaninchen Monoclonal HP67-6 unconjugated Recombinant Antibody
Produktnummer ABIN5668211
  • Target Alle CD33 (Gemtuzumab Biosimilar) Produkte
    CD33 (Gemtuzumab Biosimilar)
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    Human
    Wirt
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 3
    Monoklonal
    Konjugat
    • 3
    Dieser CD33 (Gemtuzumab Biosimilar) Antikörper ist unkonjugiert
    Applikation
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    Spezifität
    Recognises human CD33.
    Produktmerkmale

    OriginalSpeciesName: Human

    OriginalFormat: IgG4

    Aufreinigung
    Purified antibody.
    Reinheit
    > 98 % as determined by SDS-PAGE
    Endotoxin-Niveau
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    Immunogen
    Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. CD33 is a transmembrane receptor expressed on predominantly on cells of the myeloid lineage, but it can also be found on some lymphoid cells.
    Klon
    HP67-6
    Isotyp
    IgG kappa
  • Applikationshinweise
    A human IgG4 variant conjugated to derivative of the cytotoxic drug calicheamicin gamma 1, N-acetylcalicheamicin dimethyl hydrazide, has been used as a therapeutic against acute myeloid leukemia. This antibody may also be used in flow cytometry and immunofluorescence.
    Kommentare

    This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % Proclin 300.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    CD33 (Gemtuzumab Biosimilar)
    Abstract
    CD33 (Gemtuzumab Biosimilar) Produkte
    Synonyme
    SIGLEC-3 antikoerper, SIGLEC3 antikoerper, p67 antikoerper, CD33 molecule antikoerper, CD33 antikoerper
    Substanzklasse
    Biosimilar
    Hintergrund
    Siglec-3
    UniProt
    P20138
Sie sind hier:
Kundenservice