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Rekombinanter ErbB2/Her2 (Trastuzumab Biosimilar) Antikörper

Reaktivität: Human FACS, ELISA, IHC Wirt: Kaninchen Monoclonal 4D5-8 unconjugated Recombinant Antibody
Produktnummer ABIN5668227
  • Target Alle ErbB2/Her2 (Trastuzumab Biosimilar) Produkte
    ErbB2/Her2 (Trastuzumab Biosimilar)
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    Human
    Wirt
    • 1
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 4
    Monoklonal
    Konjugat
    • 4
    Dieser ErbB2/Her2 (Trastuzumab Biosimilar) Antikörper ist unkonjugiert
    Applikation
    • 3
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Immunohistochemistry (IHC)
    Spezifität
    Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30 % of invasive breast cancers and 70 % of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder.
    Produktmerkmale

    OriginalSpeciesName: Human

    OriginalFormat: IgG1

    Aufreinigung
    Purified antibody.
    Reinheit
    > 98 % as determined by SDS-PAGE
    Endotoxin-Niveau
    Endotoxin is < 1.0 EU/mg as determined by the LAL method
    Immunogen
    A431 cells (human epidermoid carcinoma) (over)expressing EGFR.
    Klon
    4D5-8
    Isotyp
    IgG kappa
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Kommentare

    This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % Proclin 300.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • Target
    ErbB2/Her2 (Trastuzumab Biosimilar)
    Abstract
    ErbB2/Her2 (Trastuzumab Biosimilar) Produkte
    Synonyme
    CD340 antikoerper, HER-2 antikoerper, HER-2/neu antikoerper, HER2 antikoerper, MLN 19 antikoerper, NEU antikoerper, NGL antikoerper, TKR1 antikoerper, erb-b2 receptor tyrosine kinase 2 antikoerper, ERBB2 antikoerper
    Substanzklasse
    Biosimilar
    Hintergrund
    CD340, Metastatic lymph node gene 19 protein (MLN 19), Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, p185HER2, EGFR
    UniProt
    P04626
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