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COMMD1 Antikörper (AA 1-190)

COMMD1 Reaktivität: Human WB, ELISA, IP Wirt: Maus Monoclonal 2A12 unconjugated
Produktnummer ABIN566862
  • Target Alle COMMD1 Antikörper anzeigen
    COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))
    Bindungsspezifität
    • 15
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-190
    Reaktivität
    • 41
    • 22
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 46
    • 10
    Maus
    Klonalität
    • 49
    • 7
    Monoklonal
    Konjugat
    • 26
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COMMD1 Antikörper ist unkonjugiert
    Applikation
    • 36
    • 20
    • 13
    • 13
    • 10
    • 8
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Verwendungszweck
    Mouse monoclonal antibody raised against a full length recombinant COMMD1.
    Sequenz
    MAAGELEGGK PLSGLLNALA QDTFHGYPGI TEELLRSQLY PEVPPEEFRP FLAKMRGILK SIASADMDFN QLEAFLTAQT KKQGGITSDQ AAVISKFWKS HKTKIRESLM NQSRWNSGLR GLSWRVDGKS QSRHSAQIHT PVAIIELELG KYGQESEFLC LEFDEVKVNQ ILKTLSEVEE SISTLISQPN
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    COMMD1 (AAH22046.1, 1 a.a. ~ 190 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Klon
    2A12
    Isotyp
    IgG2a
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1x PBS, pH 7.4
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • OHara, Simpson, Morin, Loveridge, Williams, Novo, Stark: "p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-?B subunit." in: Journal of cell science, Vol. 127, Issue Pt 17, pp. 3659-65, (2014) (PubMed).

    Schilling, Bayer, Li, Molls, Vaupel, Multhoff: "Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1?." in: PLoS ONE, Vol. 7, Issue 2, pp. e31110, (2012) (PubMed).

    Drévillon, Tanguy, Hinzpeter, Arous, de Becdelièvre, Aissat, Tarze, Goossens, Fanen: "COMMD1-mediated ubiquitination regulates CFTR trafficking." in: PLoS ONE, Vol. 6, Issue 3, pp. e18334, (2011) (PubMed).

    Vonk, Wijmenga, Berger, van de Sluis, Klomp: "Cu,Zn superoxide dismutase maturation and activity are regulated by COMMD1." in: The Journal of biological chemistry, Vol. 285, Issue 37, pp. 28991-9000, (2010) (PubMed).

    Huang, Wu, Li: "Tumor suppressor ARF promotes non-classic proteasome-independent polyubiquitination of COMMD1." in: The Journal of biological chemistry, Vol. 283, Issue 17, pp. 11453-60, (2008) (PubMed).

    Burkhead, Morgan, Shinde, Haddock, Lutsenko: "COMMD1 forms oligomeric complexes targeted to the endocytic membranes via specific interactions with phosphatidylinositol 4,5-bisphosphate." in: The Journal of biological chemistry, Vol. 284, Issue 1, pp. 696-707, (2008) (PubMed).

    Weiss, Lozoya, Tuma, Gotthardt, Reichert, Ehehalt, Stremmel, Füllekrug: "Copper-induced translocation of the Wilson disease protein ATP7B independent of Murr1/COMMD1 and Rab7." in: The American journal of pathology, Vol. 173, Issue 6, pp. 1783-94, (2008) (PubMed).

    Maine, Mao, Komarck, Burstein: "COMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligase." in: The EMBO journal, Vol. 26, Issue 2, pp. 436-47, (2007) (PubMed).

    de Bie, van de Sluis, Burstein, van de Berghe, Muller, Berger, Gitlin, Wijmenga, Klomp: "Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B." in: Gastroenterology, Vol. 133, Issue 4, pp. 1316-26, (2007) (PubMed).

  • Target
    COMMD1 (Copper Metabolism (Murr1) Domain Containing 1 (COMMD1))
    Andere Bezeichnung
    COMMD1 (COMMD1 Produkte)
    Synonyme
    C2orf5 antikoerper, MURR1 antikoerper, murr1 antikoerper, commd1 antikoerper, si:ch211-213b8.2 antikoerper, DDBDRAFT_0184206 antikoerper, DDBDRAFT_0266452 antikoerper, DDB_0184206 antikoerper, DDB_0266452 antikoerper, COMMD1 antikoerper, MGC114682 antikoerper, AI256843 antikoerper, Murr1 antikoerper, U2/Mu antikoerper, copper metabolism domain containing 1 antikoerper, copper metabolism (Murr1) domain containing 1 antikoerper, COMM domain-containing protein 1 antikoerper, copper metabolism domain containing 1 L homeolog antikoerper, COMM domain containing 1 antikoerper, COMMD1 antikoerper, commd1 antikoerper, comd1 antikoerper, Commd1 antikoerper, commd1.L antikoerper
    Hintergrund
    Full Gene Name: copper metabolism (Murr1) domain containing 1
    Synonyms: C2orf5,MGC27155,MURR1
    Gen-ID
    150684
    Pathways
    Transition Metal Ion Homeostasis
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