RAB7B Antikörper (AA 100-199)

Produktnummer ABIN567027

Produktdetails anti-RAB7B Antikörper

Target: RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Bindungsspezifität: AA 100-199

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RAB7B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Verwendungszweck: Mouse monoclonal antibody raised against a partial recombinant RAB7B.

Sequenz: DIWRGDVLAK IVPMEQSYPM VLLGNKIDLA DRKVPQEVAQ GWCREKDIPY FEVSAKNDIN VVQAFEMLAS RALSRYQSIL ENHLTESIKL SPDQSRSRCC

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: RAB7B (NP_796377, 100 a.a. ~ 199 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon: 3B3

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-RAB7B Antikörper (ABIN567027)

Margiotta, Progida, Bakke, Bucci: "Rab7a regulates cell migration through Rac1 and vimentin." in: Biochimica et biophysica acta, Vol. 1864, Issue 2, pp. 367-381, (2016) (PubMed).

Borg, Bakke, Progida: "A novel interaction between Rab7b and actomyosin reveals a dual role in intracellular transport and cell migration." in: Journal of cell science, Vol. 127, Issue 22, pp. 4927-39, (2014) (PubMed).

Zlatic, Tornieri, LHernault, Faundez: "Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells." in: Molecular biology of the cell, Vol. 22, Issue 10, pp. 1699-715, (2011) (PubMed).

Higashi, Iseki, Minegishi, Togo, Kabuta, Wada: "GIGYF2 is present in endosomal compartments in the mammalian brains and enhances IGF-1-induced ERK1/2 activation." in: Journal of neurochemistry, Vol. 115, Issue 2, pp. 423-37, (2010) (PubMed).

Zhu, Salazar, Zlatic, Fiza, Doucette, Heilman, Levey, Faundez, Lhernault: "SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery." in: Molecular biology of the cell, Vol. 20, Issue 4, pp. 1223-40, (2009) (PubMed).

Higashi, Moore, Yamamoto, Minegishi, Sato, Togo, Katsuse, Uchikado, Furukawa, Hino, Kosaka, Emson, Wada, Dawson, Dawson, Arai, Iseki: "Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in lewy body disease." in: Journal of neuropathology and experimental neurology, Vol. 68, Issue 9, pp. 994-1005, (2009) (PubMed).

Details zu RAB7B

Target: RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Andere Bezeichnung: RAB7B (RAB7B Produkte)

Hintergrund: Full Gene Name: RAB7B, member RAS oncogene family
Synonyms: MGC16212,MGC9726,RAB7

Gen-ID: 338382

NCBI Accession: NM_177403