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HIPK1 Antikörper (AA 1-100)

HIPK1 Reaktivität: Human, Maus, Affe, Makake WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5675039
  • Target Alle HIPK1 Antikörper anzeigen
    HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reaktivität
    • 53
    • 27
    • 15
    • 14
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Affe, Makake
    Wirt
    • 48
    • 5
    Kaninchen
    Klonalität
    • 49
    • 4
    Polyklonal
    Konjugat
    • 18
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HIPK1 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 24
    • 17
    • 12
    • 12
    • 7
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human, Makake, Affe, Maus
    Homologie
    Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HIPK1
    Isotyp
    IgG
    Top Product
    Discover our top product HIPK1 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    HIPK1 (Homeodomain Interacting Protein Kinase 1 (HIPK1))
    Andere Bezeichnung
    HIPK1 (HIPK1 Produkte)
    Synonyme
    HIPK1 antikoerper, myak antikoerper, nbak2 antikoerper, hipk1 antikoerper, Myak antikoerper, Nbak2 antikoerper, 1110062K04Rik antikoerper, homeodomain interacting protein kinase 1 antikoerper, homeodomain interacting protein kinase 1 L homeolog antikoerper, homeodomain interacting protein kinase 1 S homeolog antikoerper, HIPK1 antikoerper, hipk1.L antikoerper, hipk1 antikoerper, hipk1.S antikoerper, Hipk1 antikoerper
    Hintergrund

    Synonyms: Hipk 1, Hipk1, HIPK1_HUMAN, Homeodomain interacting protein kinase 1, Homeodomain interacting protein kinase 1 like protein, Homeodomain-interacting protein kinase 1, Myak, Nbak 2, Nbak2, Nuclear body associated kinase 2, Nuclear body associated kinase 2b

    Background: Serine/threonine-protein kinase involved in transcription regulation and TNF-mediated cellular apoptosis. Plays a role as a corepressor for homeodomain transcription factors. Phosphorylates DAXX and MYB. Phosphorylates DAXX in response to stress, and mediates its translocation from the nucleus to the cytoplasm. Inactivates MYB transcription factor activity by phosphorylation. Prevents MAP3K5-JNK activation in the absence of TNF. TNF triggers its translocation to the cytoplasm in response to stress stimuli, thus activating nuclear MAP3K5-JNK by derepression and promoting apoptosis. May be involved in anti-oxidative stress responses. Involved in the regulation of eye size, lens formation and retinal lamination during late embryogenesis. Promotes angiogenesis and to be involved in erythroid differentiation. May be involved in malignant squamous cell tumor formation.

    Gen-ID
    204851
    UniProt
    Q86Z02
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